EDF Health

Doublespeak is alive and well in the ACC-backed “SAB Reform Act”

Richard Denison, Ph.D., is a Senior Scientist.

George Orwell would be proud

Yesterday a Senate copycat of a House bill called the “EPA Science Advisory Board Reform Act of 2013” was introduced.  The Senate bill has yet to be made publicly available, but that didn’t stop the American Chemistry Council (ACC) from sending out its own release strongly supporting the bill, literally within minutes of the issuance of a press release by the bill’s main sponsors.

Assuming (as stated in the release) that the Senate bill is the same as the House bill, H.R. 1422, no wonder ACC loves this bill: 

  • Tired of having your companies’ scientists and hired consultants excluded from SAB panels because of conflicts of interest?  Write a bill that eliminates such a pesky rule, and then say the bill “eliminates conflicts of interest.”
  • Frustrated by the time limit placed on comments from the army of industry commenters that typically show up at SAB panel meetings?  Bar the setting of any time limit so you can stack the deck, and then say the bill “promotes fairness” and “strengthens public participation.”
  • Unhappy with how many independent academic scientists are seated on SAB panels?  Require not only that panel members be willing to devote their time to review lengthy EPA documents, but that they respond in writing to every public comment received – a massive expansion in the workload placed on panel members, given the flood of industry comments typically provided – and then say the bill “promotes transparency.”
  • Upset with academic scientists on SAB panels that receive government grants not always supporting the industry position?  Claim that they are the ones who have conflicts of interest, single them out for disclosure of their grants and contracts – with no mention of industry consultants – and then say the bill “increases disclosures” related to potential conflicts.  (An earlier version of the bill would actually have set a 10% quota for government-funded scientists on SAB panels; happily that was removed after an outcry.)
  • Want to slow down the pace of EPA risk and hazard assessments?  Require that every single such assessment be sent to SAB for review, exponentially expanding the SAB’s workload and adding months or years to the process of finalizing assessments, and then say the bill merely “enables SAB reviews” of such documents.

Despite its grand claims, the EPA SAB Reform Act is nothing more than a thinly veiled attempt by ACC and its Hill allies to heavily stack the deck in its favor when it comes to independent scientific reviews of EPA work products.

When the House bill was introduced earlier this year, more than a dozen of the country’s premier public health scientists weighed in strongly opposing the bill, as did a group of prominent environmental NGOs.  See those letters for more details.

While the bill clearly parrots the talking points of the chemical industry when it comes to peer review of government chemical assessments, it should be noted that the bill would apply to any and all aspects of SAB’s work, not just that on chemicals.  So scientists in all fields of endeavor relating to protection of health and the environment ought to be concerned.

 

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It’s a generational thing: Evidence grows that environmentally induced epigenetic changes can be passed down from one generation to the next

Richard Denison, Ph.D., is a Senior Scientist.

We’ve blogged here before about the growing evidence that environmental exposures can cause changes in gene expression – not to be confused with mutations, which are changes in the DNA itself.  We’ve noted that these changes in how and when our genes are turned on and off may actually be heritable, along with any biological or behavioral changes they induce.  That is, not only might the individual who is directly exposed suffer effects, but – and here’s the kicker – so might descendants who never experienced the original exposure.

Now, several new studies add even more evidence that epigenetic changes may be transgenerational.  In the past 10 days, the Washington Post has run articles detailing three new studies in mice, each of which strongly indicate that dietary deficiencies and environmental exposures can reprogram DNA in ways that can be passed along to reside in the DNA of the offspring of the affected individuals.  Read More »

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Making regrettable substitution a thing of the past

Michelle Harvey is a Senior Project Manager in EDF’s Corporate Partnership Program.

Regrettable substitution. Informed substitution.

The first sounds like a problem – and it is. The second is the way you avoid the first.

In the world of consumer products made from mixtures of chemicals – baby lotion, shampoo, cleaners, laundry soap – chemists seek ingredients that are effective and feasible. What they too often don’t also consider are the hazardous properties of the chemical and its risk to people.  This is in part because most chemists are not trained in toxicology.  Further, many of the biological interactions between us and the ingredients in everyday products we use on our bodies and in our homes are only now being understood.  As our understanding has grown, groups such as EDF have called for the removal of some of the more concerning chemical ingredients from store shelves.

But it’s not as simple as just taking a hazardous chemical out of a product.  While in some instances a chemical of concern can be simply eliminated, in many cases these chemicals perform a key function in a product and a replacement chemical is necessary.  If the replacement isn’t carefully considered for its own potentially deleterious effects, you can end up exchanging a problem for a problem – resulting in a regrettable substitution. 

The good news is that the path forward for identifying and making informed choices about substitutes has become a lot clearer. 

Today, EDF together with BizNGO, the Toxic Use Reduction Institute and the Lowell Center for Sustainability released The Commons Principles for Alternatives Assessment with the support of over 100 representatives of business, universities and NGOs.  This broad consensus around simple, solutions-based principles, signals a growing commitment to moving hazardous chemicals out of the supply chain and driving informed, safer innovations. 

Alternatives assessment is a process for identifying, comparing, and selecting safer alternatives to chemicals of concern based on certain chemical features including hazard, performance, and economics.  The six “Common Principles” establish key elements of informed decision-making about the chemicals in a product.  Reduce hazard. Minimize exposure. Use best available information. Require disclosure and transparency. Resolve trade-offs. Take action.  They are “common principles” because they are shared by a broad, diverse group of individuals from academia, industry and the NGO community.

In September, Walmart became the first retailer to call for informed substitution as suppliers phase out of chemical ingredients of concern in products it sells. It is EDF’s hope that the Commons Principles will be used to meet this commitment, and inform the efforts of other retailers and product manufacturers.  Smart and informed decisions guided by the Commons Principles can make products safer and regrettable, hazardous substitutions a thing of the past.

 

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Premier medical organizations sound alarm on toxic chemicals’ harm to reproductive health

Joanna Slaney is an EDF consultant.

As a mom, I know what it’s like to worry about the health and safety of my children. You want to do everything you can to protect your kids, and help them stay healthy and strong. That’s why I think most parents will want to pay attention to the statement released today from the American College of Obstetricians and Gynecologists (ACOG) and the American Society for Reproductive Medicine (ASRM). The joint opinion from two of the country’s most prestigious medical organizations details how prenatal exposure to certain chemicals is linked to miscarriages, stillbirths, and birth defects. These groups are urging ob-gyns to advocate for government policy changes needed to ensure we identify and reduce exposure to toxic environmental agents.

EDF Health is very pleased that ACOG and ASRM are expanding awareness of the serious threats toxic chemicals can pose to our health. We urge everyone, especially parents, to take a closer look at this joint statement.

EDF Health has issued the following statement: “Today’s statement from ACOG and ASRM is the latest reminder about the devastating impact toxic chemicals can have on our health,” said Dr. Sarah Vogel, Director, EDF Environmental Health. “Even more shocking is that most everyday chemicals have never been tested for safety.  Our doctors are telling us we need to fix America’s chemical laws to protect our families’ health.”

To learn more about the health impact of toxic chemicals, please go here.

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EDF comments at EPA workshop on applying systematic review methodology to IRIS assessments

Rachel Shaffer is a research assistant.

Lately, much of the attention of the environmental health community has been focused on Capitol Hill and the Lautenberg-Vitter chemical safety reform bill that would amend the antiquated Toxic Substances Control Act (TSCA). Yet significant – if somewhat esoteric – developments are underway at EPA that will also have major impacts on how the safety of chemicals is assessed.  EPA has been implementing improvements to its Integrated Risk Information System, commonly known as “IRIS.” The purpose of the IRIS program is to evaluate information on the effects of potential exposures to environmental substances and provide health hazard assessments, which are then used to support regulatory decisions across the agency.  And while it isn’t directly affected by TSCA or its reform, IRIS provides both indirect and direct support to the office at EPA that does administer TSCA.  

In other words, what happens in IRIS doesn’t stay in IRIS.

So… what’s IRIS up to? Read More »

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My mother is not Angelina Jolie

Rachel Shaffer is a research assistant.

Last week, Angelina Jolie announced that she recently had a double mastectomy: surgery to remove both of her breasts. She chose to undergo such a difficult procedure because she, like her mother who had breast cancer (and died of ovarian cancer), carries the BRCA1 gene, a genetic mutation that significantly raises her risk of breast and ovarian cancer. While Jolie does not have cancer, this surgery lowers her chances of developing the disease in the future.

That otherwise healthy women are choosing to take such drastic steps to reduce their risks of cancer demonstrates a willingness to make profound sacrifices for health.  But it also raises the question of what options for prevention are available to the millions of other women who develop breast cancer, even though they have no known genetic risk factor. Approximately 90-95% of breast cancer cases cannot be attributed to BRCA1 or other genetic mutations; these cases are triggered by various factors in a woman’s environment.  

My mother’s cancer, diagnosed ten years ago this month, falls into this category. So once again, I’m reminded of the obvious: the life of superstar Angelina Jolie does not reflect the life of my mother or the lives of the vast majority of women.  Read More »

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