Selected tags: Persistent Bioaccumulative and Toxic (PBT)

Unnerving developments in the state of the evidence on developmental neurotoxicity

Rachel Shaffer is a research assistant.

Seven years ago, leading children’s environmental health experts Philippe Grandjean and Philip Landrigan published a groundbreaking review that identified five chemicals prevalent in the environment—lead, methylmercury, polychlorinated biphenyls (PCBs), arsenic, and toluene—as developmental neurotoxicants. In their follow-up review released last week, they have added six more chemicals—manganese, fluoride, polybrominated diphenyl ethers (PBDEs), chlorpyrifos, DDT, and tetrachloroethylene (PERC)—to this list. The implications of early-life exposures to these common compounds, say the authors?  A “global silent pandemic of neurodevelopmental toxicity.”  Read More »

Posted in Emerging Science, Health Policy, Health Science | Also tagged , , , , | 2 Responses, comments now closed

This SNUR is not a SNORE!

Jennifer McPartland, Ph.D., is a Health Scientist.

Yesterday EPA finalized a significant new use rule (SNUR) under the Toxic Substances Control Act (TSCA) that requires manufacturers and importers of certain perfluorinated chemicals to notify EPA at least 90 days before commencing any “significant new use” of these chemicals.  (See below for what EPA has designated to be a “significant new use.”)

These notifications afford EPA an opportunity to evaluate the designated new uses before they start and address any risks the new uses may pose.  Read on to learn more about some novel aspects of this final rule, including the scope of what EPA has designated as significant new uses of these chemicals.  Read More »

Posted in EPA, Health Policy, Regulation | Also tagged , | Comments closed

April brings showers…and a flurry of new studies on the risks of perfluorinated chemicals

Rachel Shaffer is a research assistant.

What do waterproof jackets, car wax, and non-stick pans have in common?

Aside from being great Father’s Day presents (Dad, I’m thinking ahead this year!), they also all are made with perfluorinated compounds, or PFCs. There are hundreds of different PFCs, and their oil- and water-resistant properties make them useful in a variety of products, from cookware and carpets to food-packaging and electronics.  

Unfortunately, these chemicals have less desirable properties as well. Thanks to their strong molecular bonds, PFCs do not readily break down; they persist in the environment and in our bodies. And, widespread use has led to extensive human exposure. The Centers for Disease Control’s (CDC) human biomonitoring program, the National Health and Nutrition Examination Survey (NHANES), detected four types of PFCs in over 98% of samples representative of the U.S. population collected in 2003-2004.  

Two of the compounds detected in NHANES, perfluorooctane sulfonic acid (PFOS) and perfluorootanoic acid (PFOA), are the focus of three new studies published this month in Environmental Health Perspectives. These studies, one reporting an association with osteoarthritis in women, another an association with semen quality in men, and a third an association with asthma in children, add to a growing concern about the potential adverse effects of these ubiquitous chemicals.

What follows is a brief overview of the findings of these new studies.  Read More »

Posted in Emerging Science, Health Policy, Health Science | Also tagged , | Comments closed

ECHA raises its sights: Several recent additions to the REACH Candidate List set precedents

Alissa Sasso is a Chemicals Policy Fellow.

The European Union is maintaining a steady pace as it works to address chemicals of concern: Last month, the European Chemicals Agency (ECHA) added 54 Substances of Very High Concern (SVHCs) to the Candidate List for Authorisation under its REACH Regulation, bringing the total number of substances on the list to 138. ECHA posted a press release listing the new SVHCs and describing some of the more interesting additions, which we’ve highlighted below.

For 23 of the additions, REACH’s Member State Committee (MSC) reviewed public comments during the comment period on draft SVHC proposals before voting unanimously to add all of them onto the Candidate List. The other 31 new additions were not challenged during the public comment period, and hence moved directly onto the candidate list without MSC consultation.

The majority of the new SVHCs, like most substances already on the list, are classified as carcinogen, mutagenic and/or toxic to reproduction (CMRs).  But it’s with the other new listings that it gets really interesting.  Read More »

Posted in EU REACH, Health Policy | Also tagged , , | Comments closed

Doing its best under a flawed law: 35 groups file comments supporting EPA efforts to reduce exposure to toxic flame retardants

Jennifer McPartland, Ph.D., is a Health Scientist. Richard Denison, Ph.D., is a Senior Scientist.

Today Environmental Defense Fund and Earthjustice, joined by 33 other health and environmental groups, filed comments that urge the U.S. Environmental Protection Agency (EPA) to swiftly move forward with two proposed actions to regulate a group of toxic flame retardants called PBDEs (polybrominated diphenyl ethers). 

The first proposed rule would require anyone intending to begin production, processing or import of any PBDE, or a product containing one, to notify EPA before doing so.  This would give the agency an opportunity to evaluate the risks of the proposed activity and if necessary take action to restrict or prohibit it.  The second proposed rule would require anyone who continues after 2013 to produce, process or import any PBDE, or a product containing one, to conduct extensive tests needed to allow EPA to determine the risks posed by those ongoing activities.   Read More »

Posted in EPA, Health Policy, Regulation | Also tagged , , , , | Comments closed

The truth will out: Chemical industry’s deceptive tactics are eventually exposed

Richard Denison, Ph.D., is a Senior Scientist.

It’s hard not to get cynical in Washington, DC these days.  Just this past week, the American Chemistry Council (ACC) hosted an ice cream social on Capitol Hill – I kid you not.  ACC’s beckoning slogan:  “Join and learn about the benefits of chlorine chemistry and enjoy a tasty treat.”  I’m told hundreds of House staffers partook of this propaganda fest, at least the tasty treat part.  My initial reaction?  How can health and environmental advocates hope to compete?  Especially if one can successfully curry favor merely by offering a scoop of a staffer’s favorite flavor.

But just as I began to despair, Part I of a major exposé on a far more serious campaign of deception by the chemical industry ran on the front page of the Sunday Chicago Tribune.  (Actually, the article occupies virtually the entire front page of today’s edition.)   Read More »

Posted in Health Science, Industry Influence | Also tagged , , , , | 1 Response, comments now closed

A ray of sunlight up ahead: ECHA to release more information through REACH dossiers

Allison Tracy is a Chemicals Policy Fellow.

After many months of increasing the quantity but not the quality of dossiers available to the public for chemicals registered under REACH, the European Chemicals Agency (ECHA) has recently announced two improvements.  (REACH is the European Union’s regulation for the Registration, Evaluation, Authorization and Restriction of Chemicals.)  According to the agency, the public will soon have access to more data from the dossiers that were submitted by companies as part of the first wave of REACH’s Registration process.

In a press release issued a couple of weeks ago, ECHA announced that it will publish information from registered chemicals’ Safety Data Sheets – including the identity of the registrant and whether the chemical was found to be Persistent, Bioaccumulative and Toxic (PBT).  And last week, ECHA said it will also publish (by June) the aggregate production volume ranges (called “tonnage bands”) for chemicals registered under REACH.  These decisions will improve ECHA’s record on disclosure and transparency by increasing the amount of both hazard and exposure data available to the public on chemicals in use.  Read More »

Posted in EU REACH, Health Policy | Also tagged , | Comments closed

ECHA gives a CoRAP: REACH substance evaluation kicks off with list of target chemicals

Allison Tracy is a Chemicals Policy Fellow.

Posts to this blog concerning REACH – the European Union’s regulation for the Registration, Evaluation, Authorization and Restriction of Chemicals – have dealt mainly with the “R” and “A”.  A few weeks ago, the European Chemicals Agency (ECHA) took a first big step to capitalize on the “E” (Evaluation).

Specifically, the final 2012-2014 Community Rolling Action Plan (CoRAP) was published on February 29th (see ECHA’s press release).  After many months of consultation with the Member States, ECHA has released the list of 90 chemicals that will be the first to undergo REACH’s substance evaluation process in 2012, 2013, and 2014.

Existing data guided the prioritization process that led to the production of this list, but REACH’s authorities granted for substance evaluation will allow ECHA and the Member States to gather new information to fill data gaps.  This new information will help to improve both governmental and public knowledge about the risks these chemicals may pose to human health and the environment.  Read More »

Posted in EU REACH, Health Policy | Also tagged , , , , , , , , | Comments closed

REACH starts to earn its "A": 20 chemicals headed to the Candidate List and 13 to Authorization

Allison Tracy is a Chemicals Policy Fellow. Richard Denison, Ph.D., is a Senior Scientist.

The European Chemicals Agency (ECHA) has been busy this week implementing the EU's chemical regulation, REACH (short for Registration, Evaluation, Authorization and Restriction of Chemicals).

On Monday, ECHA announced it has added 20 more Substances of Very High Concern (SVHCs) to REACH's Candidate List.  These SVHCs are now eligible for later addition to Annex XIV, the list of SVHCs subject to Authorization.

Separately, the agency today forwarded its final recommendation that 13 chemicals already on the Candidate List be formally added to Annex XIV.  (We had blogged earlier about ECHA's initial recommendation proposing these 13 SVHCs for Authorization.)  If the European Commission confirms this addition, after a specified sunset date, the use of these will be allowed only if specifically authorized by EU authorities.  Read More »

Posted in EU REACH, Health Policy | Also tagged , , , , , , | Comments closed

Expansion of my critique of the ACC tool's persistence and bioaccumulation criteria

Richard Denison, Ph.D., is a Senior Scientist.

I want to clarify and expand on the discussion in my last post on ACC’s selection of criteria for persistence (P) and bioaccumulation (B).  The bottom line remains the same:  ACC selected the least conservative values proposed by any authoritative body for these parametersRead More »

Posted in Health Policy | Also tagged , | Comments closed
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