Selected tags: diabetes

A new power couple: The combined impact of the microbiome and chemical exposures on disease susceptibility (Part 2 of 2)

Allison Tracy is a Chemicals Policy Fellow. EDF Health Scientist Dr. Jennifer McPartland and Senior Scientist Dr. Richard Denison contributed to this post.

In Part 1 of this two-part post, I reviewed scientific evidence that the gut microbiome interacts with ingested chemicals to influence susceptibility to obesity and diabetes.  This hypothesis is the focus of a recent review article by Suzanne Snedeker and Anthony Hay.  Having reviewed evidence of the link between the microbiome and obesity and diabetes as well as the link between chemical exposures and obesity and diabetes, we now proceed to address this question:  Can the gut microbiome act in concert with ingested synthetic chemicals to predispose people to obesity and diabetes?

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A new power couple: The combined impact of the microbiome and chemical exposures on disease susceptibility (Part 1 of 2)

Allison Tracy is a Chemicals Policy Fellow.  EDF Health Scientist Dr. Jennifer McPartland and Senior Scientist Dr. Richard Denison contributed to this post.

When you’re standing at the kitchen counter this holiday season wrestling with the nebulous world of weight gain, think about synthetic chemicals.  A good number of them are in you.  And studies show that some of them are pretty busy in there, interacting with various biological systems – including your metabolism.

But they’re not the only show in town.  Microbes are busy in your gut doing important things like digesting food and degrading harmful compounds.  But could they also influence the size of your love handles?  New science suggests that these microbes—in concert with certain chemicals—may have just this effect.

It is becoming increasingly clear that it’s not just your genes and your self control that determine your risk for obesity and related complications like diabetes.  Environmental factors are a big part of the equation, and those factors just might extend to synthetic chemicals to which you’re exposed, such as the flame retardants in your furniture and the plasticizers in food can linings.  Read More »

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Could these chemicals make my grandchild look fat?

Richard Denison, Ph.D., is a Senior Scientist.

In an earlier post by my colleague Dr. Jennifer McPartland, she described new research that is linking certain chemical exposures to the rising epidemic of diabetes and obesity.  Some of that research, mainly conducted in laboratory animals, is revealing that when a mother is exposed to such chemicals before or during pregnancy, her offspring are more likely to suffer from diabetes and obesity as they mature.

How might such a proclivity toward development of diabetes and obesity later in life be transferred from one generation to the next, from mother to child?

In a word, epigenetics.   Read More »

Posted in Emerging Science, Health Science| Also tagged , , | 1 Response, comments now closed

Testing for endocrine disruption: Are we there yet?

Cal Baier-AndersonCal Baier-Anderson, Ph.D., is a Health Scientist.

After long delays, the EPA’s Office of Pesticide Programs recently issued endocrine disruptor screening test orders for dozens of high-priority pesticide ingredients.  Endocrine disruptors are chemicals capable of interfering with the action of hormones that regulate biological processes such as development, growth, reproduction and metabolism.  The test orders require pesticide manufacturers to evaluate their chemicals using a specific battery of tests.

Identifying which chemicals are endocrine disruptors can help protect people and the environment from harmful exposures.  So, with test orders now in the hands of pesticide manufacturers, will we finally get the data we need? Read More »

Posted in Emerging Testing Methods, Health Science| Also tagged , , , , , , | 2 Responses, comments now closed
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