Tag Archives: Carcinogenic Mutagenic or Toxic for Reproduction (CMR)

Is BPA a carcinogen?

Sarah Vogel, Ph.D., is Director of EDF's Health Program.

Add liver cancer—a childhood cancer on the rise in the US—to the growing list of potential health effects associated with bisphenol A (BPA) exposure that are under scrutiny by researchers.  A recent study by scientists at the University of Michigan, published in Environmental Health Perspectives, is the first ever to report a dose-dependent, statistically significant relationship between perinatal (before and just after birth) exposures to environmentally relevant levels of BPA and development of cancerous liver tumors later in life.

There are three particularly notable features of this study: first, the dose levels used; second, the timing of when those doses were delivered; and third, the age at which effects were observed.  Read More »

Posted in Emerging Science, Health Science| Also tagged , | Comments closed

Two safer chemicals initiatives garner national headlines: Mind the Store campaign and The Safe Chemicals Act of 2013

Richard Denison, Ph.D., is a Senior Scientist.

This morning, two major daily newspapers carried stories on initiatives to ensure the safety of products containing chemicals to which people are increasingly exposed in their daily lives.

A story in USA Today covers the launch of Mind the Store, a campaign that asks the top 10 retailers in the country to develop and make public their plans to address toxic chemicals in the consumer products they sell. 

Also today, the Philadelphia Inquirer ran a story on the introduction of the Safe Chemicals Act of 2013 in the U.S. Senate, which would amend the core provisions of the Toxic Substances Control Act (TSCA) for the first time since its passage 37 years ago. 

See more information on each of these initiatives below.  Read More »

Posted in Health Policy, Markets and Retail, TSCA Reform| Also tagged , , , | Comments closed

The chemical industry says formaldehyde and styrene don’t cause cancer. Only one of 52 scientists agree.

Richard Denison, Ph.D., is a Senior Scientist.

Last week, the National Academy of Sciences (NAS) held a joint meeting of its two panels that are charged with reviewing the listings of formaldehyde and styrene as carcinogens in the 12th Report on Carcinogens, which was released in June 2011.

The 12th Report on Carcinogens (RoC) is the latest edition of a Congressionally mandated report developed by the National Toxicology Program (NTP).  It upgraded formaldehyde to the status of “known to be a human carcinogen,” and for the first time listed styrene as “reasonably anticipated to be a human carcinogen.”  That put the chemical industry into a real tizzy, what with the threat these listings pose to its profits from the huge volumes of these cash cows sold each year, not to mention the huge potential liability it faces.

Never one to go down lightly, the American Chemistry Council (ACC) has launched an all-out assault on the NTP and the RoC.  It is waging battle not only with the executive branch, but also in the courts and in Congress.  In late 2011, it managed to get its allies in Congress to slip into the Consolidated Appropriations Act of 2012, without any debate, a rider that mandated the NAS reviews of the formaldehyde and styrene listings in the 12th RoC that are now underway.

ACC also pushed legislation in the last Congress to shut down all funding for the RoC until the reviews are completed; failing on that front, earlier this month it demanded that NTP cease all work on the next (13th) edition of the RoC.  (For more background, see previous blog posts by EDF and NRDC.)

Lost in all this kerfluffle, however, are these salient facts:

  • The formaldehyde and styrene listings are the outcome of one of the most extensive scientific assessment processes on the planet, entailing reviews by four separate groups of expert scientists for each chemical.
  • ACC as well as the public had at least three separate formal opportunities for providing input to these expert bodies.
  • Of a total of 52 votes cast by these scientific panels on the NTP’s recommended listings, 51 of those votes supported the recommendations and only one opposed them. Read More »
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The beat goes on with 13 new additions to the Candidate List under REACH

Allison Tracy is a Chemicals Policy Fellow. Richard Denison, Ph.D., is a Senior Scientist.

The number of chemicals identified as “substances of very high concern” (SVHCs) in the European Union continues to grow.  With today’s addition of 13 new chemicals, there are now 84 entries (representing 92 Chemical Abstract Service (CAS) registration numbers) on REACH’s Candidate List for Substances of Very High Concern for Authorisation.

The European Chemicals Agency (ECHA) added the 13 chemicals based on each chemical’s classification as Carcinogenic, Mutagenic, or Toxic for Reproduction (CMR).  [UPDATE:  Of the new batch, two are among the 83 TSCA workplan chemicals recently identified by EPA as priorities for risk assessment, and five were reported as being in U.S. commerce in 2006.  With the new addition, a total of 48 of the 92 CAS numbers on the Candidate List were reported as in commerce in the U.S. in 2006.  Additionally, 20 of the 92 CAS numbers on the Candidate List are included among the TSCA workplan chemicals.] Read More »

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ECHA gives a CoRAP: REACH substance evaluation kicks off with list of target chemicals

Allison Tracy is a Chemicals Policy Fellow.

Posts to this blog concerning REACH – the European Union’s regulation for the Registration, Evaluation, Authorization and Restriction of Chemicals – have dealt mainly with the “R” and “A”.  A few weeks ago, the European Chemicals Agency (ECHA) took a first big step to capitalize on the “E” (Evaluation).

Specifically, the final 2012-2014 Community Rolling Action Plan (CoRAP) was published on February 29th (see ECHA’s press release).  After many months of consultation with the Member States, ECHA has released the list of 90 chemicals that will be the first to undergo REACH’s substance evaluation process in 2012, 2013, and 2014.

Existing data guided the prioritization process that led to the production of this list, but REACH’s authorities granted for substance evaluation will allow ECHA and the Member States to gather new information to fill data gaps.  This new information will help to improve both governmental and public knowledge about the risks these chemicals may pose to human health and the environment.  Read More »

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REACH starts to earn its "A": 20 chemicals headed to the Candidate List and 13 to Authorization

Allison Tracy is a Chemicals Policy Fellow. Richard Denison, Ph.D., is a Senior Scientist.

The European Chemicals Agency (ECHA) has been busy this week implementing the EU's chemical regulation, REACH (short for Registration, Evaluation, Authorization and Restriction of Chemicals).

On Monday, ECHA announced it has added 20 more Substances of Very High Concern (SVHCs) to REACH's Candidate List.  These SVHCs are now eligible for later addition to Annex XIV, the list of SVHCs subject to Authorization.

Separately, the agency today forwarded its final recommendation that 13 chemicals already on the Candidate List be formally added to Annex XIV.  (We had blogged earlier about ECHA's initial recommendation proposing these 13 SVHCs for Authorization.)  If the European Commission confirms this addition, after a specified sunset date, the use of these will be allowed only if specifically authorized by EU authorities.  Read More »

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