{"id":5887,"date":"2016-12-15T14:07:03","date_gmt":"2016-12-15T19:07:03","guid":{"rendered":"http:\/\/blogs.edf.org\/health\/?p=5887"},"modified":"2017-01-25T09:46:21","modified_gmt":"2017-01-25T14:46:21","slug":"perchlorate-regulation-critical-opportunities-for-epa-and-fda-to-protect-childrens-brains","status":"publish","type":"post","link":"https:\/\/blogs.edf.org\/health\/2016\/12\/15\/perchlorate-regulation-critical-opportunities-for-epa-and-fda-to-protect-childrens-brains\/","title":{"rendered":"Perchlorate regulation: Critical opportunities for EPA and FDA to protect children\u2019s brains"},"content":{"rendered":"<p><a href=\"https:\/\/www.edf.org\/people\/tom-neltner\"><em><strong>Tom Neltner, J.D.<\/strong><\/em><\/a><em><strong>,\u00a0<\/strong><\/em><strong>is Chemicals Policy Director<\/strong><\/p>\n<p><a href=\"https:\/\/www.cdc.gov\/biomonitoring\/Perchlorate_BiomonitoringSummary.html\">All Americans<\/a> who have been tested have perchlorate in their bodies. <a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/27029550\">Perchlorate threatens fetal and child brain development<\/a> by impairing the thyroid\u2019s ability to transport iodine in the diet into the gland to make a thyroid hormone, known as T4, that is <a href=\"http:\/\/pediatrics.aappublications.org\/content\/117\/6\/2290.long\">essential to brain development<\/a>. Both the Environmental Protection Agency (EPA) and the Food and Drug Administration (FDA) are scheduled to make decisions in 2017 that could significantly reduce exposure to this hazardous chemical.<\/p>\n<p>Based on <a href=\"https:\/\/www.regulations.gov\/document?D=EPA-HQ-OW-2016-0438-0002\">statements in a new report by EPA<\/a>, we estimate that at least 20% of pregnant women are already iodine deficient, resulting in T4 levels that put the fetuses\u2019 developing brains at risk. For this population of pregnant women, any perchlorate exposure results in an even greater risk of impaired brain development in their children and potentially a lifetime of behavioral and learning difficulties.<\/p>\n<p>This is why it is critical that our public health agencies take actions to reduce exposure to perchlorate with a focus on this vulnerable population. There are three key decisions to be made in the coming year:<\/p>\n<ol>\n<li>EPA will decide in January 2017 <a href=\"http:\/\/www.hazenandsawyer.com\/uploads\/downloads\/Perchlorate_bromate_and_chlorate_in_hypochlorite_solutions.pdf\">whether hypochlorite bleach, an antimicrobial pesticide, degrades to perchlorate<\/a> in significant amounts. If EPA agrees it does, the agency must set standards to limit that degradation as part of its 15-year update to the pesticide\u2019s registration. Bleach is a widely-used disinfectant in food manufacturing facilities and <a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/27029550\">likely a significant source of perchlorate<\/a> in contaminated foods. Research shows that reducing hypochlorite concentration limits degradation and this, coupled with expiration dates on the product would significantly reduce exposure to perchlorate.<\/li>\n<li>FDA will decide <a href=\"https:\/\/blogs.edf.org\/health\/2016\/03\/31\/perclorate-lawsuit\/\">whether perchlorate should continue allowing perchlorate to be added to plastic packaging for dry food at levels up to 12,000 ppm<\/a> to reduce buildup of static charges. The agency has evidence that the perchlorate migrates from the packaging into food, especially when it flows in and out of the container. In response to a lawsuit filed by public interest organizations, <a href=\"https:\/\/blogs.edf.org\/health\/wp-content\/blogs.dir\/11\/files\/2016\/12\/FDA-Perchlorate-Order-and-Joint-Motion-8-30-16.pdf\">FDA told a court<\/a> that it aims to make a final decision by the end of March 2017. A <a href=\"http:\/\/www.nature.com\/jes\/journal\/v18\/n6\/full\/7500648a.html\">2008 report<\/a> by FDA indicated that almost 75% of all food types are contaminated with perchlorate.<\/li>\n<li><a href=\"https:\/\/blogs.edf.org\/health\/wp-content\/blogs.dir\/11\/files\/2016\/12\/Perchlorate-NRDC-v-EPA-2-16-cv-01251-ER-Consent-Decree-Entered-10-19-16.pdf\">EPA told a court<\/a> that it will complete external peer review of a dose-response model in October 2017 and sign a proposed rule to regulate perchlorate in drinking water a year later. This model is a critical step in <a href=\"https:\/\/www.regulations.gov\/document?D=EPA-HQ-OW-2009-0297-0675\">establishing a drinking water standard for perchlorate<\/a> pursuant to its 2011 determination that an enforceable standard was necessary under the Safe Drinking Water Act. The perchlorate is most likely from contaminated source waters (e.g. from military and defense industry activities and some fertilizer use in agricultural regions) or from degradation of hypochlorite bleach used to disinfect water. EPA acted in response to a lawsuit by the Natural Resources Defense Council.<\/li>\n<\/ol>\n<p>To guide their decision-making, FDA and EPA collaborated to <a href=\"https:\/\/www.regulations.gov\/document?D=EPA-HQ-OW-2016-0438-0004\">develop a biologically-based dose-response model<\/a> to predict T4 levels in pregnant women, fetuses, and infants exposed to perchlorate. EDF and NRDC submitted <a href=\"https:\/\/www.regulations.gov\/document?D=EPA-HQ-OW-2016-0438-0014\">joint comments<\/a> on the model and the <a href=\"https:\/\/www.regulations.gov\/document?D=EPA-HQ-OW-2016-0438-0002\">summary report <\/a>requesting that EPA ensure protection of fetuses during the first two trimesters for pregnant women with serious iodine deficiencies.\u00a0 These fetuses are particularly vulnerable because their thyroids is not yet functioning. The current fetal model only considers the third trimester when the fetus has a functioning thyroid. The current model fails to adequately protect their vulnerable subpopulations, falling shot of both the <a href=\"https:\/\/yosemite.epa.gov\/sab\/sabproduct.nsf\/02ad90b136fc21ef85256eba00436459\/86E44EE7F27EEC1A85257B7B0060F364\/$File\/EPA-SAB-13-004-unsigned2.pdf\">EPA&#8217;s Science Advisory Board recommendation<\/a> and the <a href=\"http:\/\/uscode.house.gov\/view.xhtml?hl=false&amp;edition=prelim&amp;req=granuleid%3AUSC-prelim-title42-section300g-1&amp;num=0&amp;saved=%7CKHRpdGxlOjQyIHNlY3Rpb246MzAwZy01IGVkaXRpb246cHJlbGltKQ%3D%3D%7C%7C%7C0%7Cfalse%7Cprelim\">Safe Drinking Water Act requirements<\/a>.<\/p>\n<p>For decades, federal agencies have been <a href=\"https:\/\/www.gpo.gov\/fdsys\/pkg\/FR-1997-04-23\/pdf\/97-10695.pdf\">charged with protecting children from environmental health risks<\/a> with the recognition that they are uniquely vulnerable to chemical exposures. The upcoming decisions on perchlorate present critical opportunities to protect what many of us value the most\u2014our children\u2019s health and their ability to learn and thrive to their fullest potential.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Tom Neltner, J.D.,\u00a0is Chemicals Policy Director All Americans who have been tested have perchlorate in their bodies. Perchlorate threatens fetal and child brain development by impairing the thyroid\u2019s ability to transport iodine in the diet into the gland to make a thyroid hormone, known as T4, that is essential to brain development. Both the Environmental &#8230;<\/p>\n","protected":false},"author":69548,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[114081,56100,69,114082,1,44,114107,56096],"tags":[104,91732,68,91633,91731,91734,423,91729,91730],"coauthors":[],"class_list":["post-5887","post","type-post","status-publish","format-standard","hentry","category-drinking-water","category-emerging-science","category-fda","category-food","category-general-interest","category-policy","category-perchlorate","category-omboira","tag-drinking-water","tag-dry-food","tag-epa","tag-fda","tag-hypochlorite","tag-model","tag-packaging","tag-perchlorate","tag-sdwa"],"acf":[],"aioseo_notices":[],"aioseo_head":"\n\t\t<!-- All in One SEO 4.9.9 - aioseo.com -->\n\t<meta name=\"description\" content=\"Tom Neltner, J.D., is Chemicals Policy Director All Americans who have been tested have perchlorate in their bodies. 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Perchlorate threatens fetal and child brain development by impairing the thyroid\u2019s ability to transport iodine in the diet into the gland to make a thyroid hormone, known as T4, that is essential to brain development. 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Perchlorate threatens fetal and child brain development by impairing the thyroid\u2019s ability to transport iodine in the diet into the gland to make a thyroid hormone, known as T4, that is essential to brain development. Both the Environmental","og:url":"https:\/\/blogs.edf.org\/health\/2016\/12\/15\/perchlorate-regulation-critical-opportunities-for-epa-and-fda-to-protect-childrens-brains\/","article:section":"Drinking Water","article:published_time":"2016-12-15T19:07:03+00:00","article:modified_time":"2017-01-25T14:46:21+00:00","article:publisher":"https:\/\/www.facebook.com\/edfhealth","twitter:card":"summary_large_image","twitter:site":"@EDFHealth","twitter:title":"Perchlorate regulation: Critical opportunities for EPA and FDA to protect children\u2019s brains - EDF Health","twitter:description":"Tom Neltner, J.D., is Chemicals Policy Director All Americans who have been tested have perchlorate in their bodies. Perchlorate threatens fetal and child brain development by impairing the thyroid\u2019s ability to transport iodine in the diet into the gland to make a thyroid hormone, known as T4, that is essential to brain development. Both the Environmental","twitter:creator":"@EDFHealth"},"aioseo_meta_data":{"post_id":"5887","title":null,"description":null,"keywords":null,"keyphrases":null,"primary_term":null,"canonical_url":null,"og_title":null,"og_description":null,"og_object_type":"default","og_image_type":"content","og_image_url":null,"og_image_width":null,"og_image_height":null,"og_image_custom_url":null,"og_image_custom_fields":null,"og_video":null,"og_custom_url":null,"og_article_section":"Drinking Water","og_article_tags":null,"twitter_use_og":true,"twitter_card":"default","twitter_image_type":"default","twitter_image_url":null,"twitter_image_custom_url":null,"twitter_image_custom_fields":null,"twitter_title":null,"twitter_description":null,"schema":{"blockGraphs":[],"customGraphs":[],"default":{"data":{"Article":[],"Course":[],"Dataset":[],"FAQPage":[],"Movie":[],"Person":[],"Product":[],"ProductReview":[],"Car":[],"Recipe":[],"Service":[],"SoftwareApplication":[],"WebPage":[]},"graphName":"","isEnabled":true},"graphs":[],"defaultGraph":"","defaultPostTypeGraph":""},"schema_type":"default","schema_type_options":null,"pillar_content":false,"robots_default":true,"robots_noindex":false,"robots_noarchive":false,"robots_nosnippet":false,"robots_nofollow":false,"robots_noimageindex":false,"robots_noodp":false,"robots_notranslate":false,"robots_max_snippet":null,"robots_max_videopreview":null,"robots_max_imagepreview":"large","priority":null,"frequency":null,"local_seo":null,"breadcrumb_settings":null,"limit_modified_date":false,"ai":null,"created":"2022-09-30 15:05:53","updated":"2025-06-06 01:29:40","seo_analyzer_scan_date":null},"aioseo_breadcrumb":"<div class=\"aioseo-breadcrumbs\"><span class=\"aioseo-breadcrumb\">\n\t\t\t<a href=\"https:\/\/blogs.edf.org\/health\" title=\"Home\">Home<\/a>\n\t\t<\/span><span class=\"aioseo-breadcrumb-separator\">&raquo;<\/span><span class=\"aioseo-breadcrumb\">\n\t\t\t<a href=\"https:\/\/blogs.edf.org\/health\/category\/policy\/\" title=\"Health policy\">Health policy<\/a>\n\t\t<\/span><span class=\"aioseo-breadcrumb-separator\">&raquo;<\/span><span class=\"aioseo-breadcrumb\">\n\t\t\t<a href=\"https:\/\/blogs.edf.org\/health\/category\/policy\/omboira\/\" title=\"Regulation\">Regulation<\/a>\n\t\t<\/span><span class=\"aioseo-breadcrumb-separator\">&raquo;<\/span><span class=\"aioseo-breadcrumb\">\n\t\t\tPerchlorate regulation: Critical opportunities for EPA and FDA to protect children\u2019s brains\n\t\t<\/span><\/div>","aioseo_breadcrumb_json":[{"label":"Home","link":"https:\/\/blogs.edf.org\/health"},{"label":"Health policy","link":"https:\/\/blogs.edf.org\/health\/category\/policy\/"},{"label":"Regulation","link":"https:\/\/blogs.edf.org\/health\/category\/policy\/omboira\/"},{"label":"Perchlorate regulation: Critical opportunities for EPA and FDA to protect children\u2019s brains","link":"https:\/\/blogs.edf.org\/health\/2016\/12\/15\/perchlorate-regulation-critical-opportunities-for-epa-and-fda-to-protect-childrens-brains\/"}],"_links":{"self":[{"href":"https:\/\/blogs.edf.org\/health\/wp-json\/wp\/v2\/posts\/5887","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/blogs.edf.org\/health\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/blogs.edf.org\/health\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/blogs.edf.org\/health\/wp-json\/wp\/v2\/users\/69548"}],"replies":[{"embeddable":true,"href":"https:\/\/blogs.edf.org\/health\/wp-json\/wp\/v2\/comments?post=5887"}],"version-history":[{"count":0,"href":"https:\/\/blogs.edf.org\/health\/wp-json\/wp\/v2\/posts\/5887\/revisions"}],"wp:attachment":[{"href":"https:\/\/blogs.edf.org\/health\/wp-json\/wp\/v2\/media?parent=5887"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/blogs.edf.org\/health\/wp-json\/wp\/v2\/categories?post=5887"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/blogs.edf.org\/health\/wp-json\/wp\/v2\/tags?post=5887"},{"taxonomy":"author","embeddable":true,"href":"https:\/\/blogs.edf.org\/health\/wp-json\/wp\/v2\/coauthors?post=5887"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}