{"id":3031,"date":"2014-02-09T17:16:56","date_gmt":"2014-02-09T22:16:56","guid":{"rendered":"http:\/\/blogs.edf.org\/health\/?p=3031"},"modified":"2024-02-12T11:01:34","modified_gmt":"2024-02-12T16:01:34","slug":"a-full-month-after-west-virginia-spill-many-questions-linger-along-with-the-chemicals-distinctive-odor","status":"publish","type":"post","link":"https:\/\/blogs.edf.org\/health\/2014\/02\/09\/a-full-month-after-west-virginia-spill-many-questions-linger-along-with-the-chemicals-distinctive-odor\/","title":{"rendered":"A full month after West Virginia spill, many questions linger &#8230; along with the chemical\u2019s distinctive odor"},"content":{"rendered":"<p><em>Richard Denison, Ph.D.<\/em><em>,<\/em> is a Senior Scientist.<\/p>\n<p><span style=\"font-size: medium\"><span style=\"color: #000000\"><span style=\"font-family: Calibri\">Today marks exactly a month since what is now said to be 10,000 gallons of \u201ccrude MCHM\u201d \u2013 mixed with what was later found to have included other chemicals \u2013 spilled into West Virginia\u2019s Elk River, contaminated 1,700 miles of piping in the water distribution system for nine counties, and disrupted the lives of hundreds of thousands of the state\u2019s residents.\u00a0 <\/span><\/span><\/span><\/p>\n<p><span style=\"font-size: medium\"><span style=\"color: #000000\"><span style=\"font-family: Calibri\">Despite declining levels of the chemical in the water being fed into the distribution system, late this past week five area schools were closed due to detection of the distinctive licorice-like odor of MCHM and multiple reports of symptoms such as eye irritation, nausea and dizziness among students and staff.<\/span><\/span><\/span><\/p>\n<p><span style=\"color: #000000;font-family: Calibri;font-size: medium\">The <\/span><a href=\"http:\/\/www.dhsem.wv.gov\/Pages\/WV-American-Water-Emergency.aspx\"><span style=\"color: #0000ff;font-family: Calibri;font-size: medium\">latest sampling data<\/span><\/a><span style=\"font-family: Calibri\"><span style=\"font-size: medium\"><span style=\"color: #000000\"> (for February 7 and 8) at locations such as area fire hydrants and hospitals and at schools shows that MCHM is at non-detect levels (&lt;10 parts per billion) in most samples, but the chemical is still being detected in a minority of the samples despite extensive flushing.\u00a0 Despite repeated calls to do so, officials appear to have yet to conduct any sampling of taps in residents\u2019 homes.<\/span><\/span><\/span><\/p>\n<p><span style=\"color: #000000;font-family: Calibri;font-size: medium\">This past week also featured a press conference by state and federal officials seeking to explain their response to the spill (a video of the entire press conference is <\/span><a href=\"http:\/\/www.wchstv.com\/newsroom\/rawnews\/\"><span style=\"color: #0000ff;font-family: Calibri;font-size: medium\">available in four parts here<\/span><\/a><span style=\"font-family: Calibri\"><span style=\"font-size: medium\"><span style=\"color: #000000\">; it\u2019s worth watching).\u00a0 <em>[UPDATE 3\/29\/14:\u00a0 As this link no longer works, here are updated links to <a href=\"http:\/\/www.wchstv.com\/newsroom\/rawnews\/raw140205_156.shtml\">Part 1<\/a>, <a href=\"http:\/\/www.wchstv.com\/newsroom\/rawnews\/raw140205_155.shtml\">Part 2<\/a>, <a href=\"http:\/\/www.wchstv.com\/newsroom\/rawnews\/raw140205_154.shtml\">Part 3<\/a> and <a href=\"http:\/\/www.wchstv.com\/newsroom\/rawnews\/raw140205_153.shtml\">Part 4<\/a> of the press conference.]<\/em><\/span><\/span><\/span><\/p>\n<p><a href=\"http:\/\/www.wvgazette.com\/News\/201402080047\"><span style=\"color: #0000ff\"><span style=\"font-size: medium\"><span style=\"font-family: Calibri\">Today\u2019s <i>Charleston Gazette<\/i><\/span><\/span><\/span><\/a><span style=\"font-family: Calibri\"><span style=\"font-size: medium\"><span style=\"color: #000000\"> features the latest in a long series of outstanding front-line reports by Ken Ward, Jr., and his colleagues, who have closely followed every twist and turn of both the spill and the government\u2019s response to it.\u00a0 Today\u2019s article makes clear the extent to which federal officials were winging it in the hours and days after the spill was discovered as they rushed to set a \u201csafe\u201d level for MCHM in tap water.<\/span><\/span><\/span><\/p>\n<p><span style=\"font-family: Calibri\"><span style=\"font-size: medium\"><span style=\"color: #000000\">In this post I\u2019ll delve a little deeper into CDC\u2019s rush to set the \u201csafe\u201d level and the many ways in which CDC inadequately accounted for major data gaps and uncertainties.\u00a0 I\u2019ll end by saying what I think CDC should have done instead.\u00a0 <!--more--><\/span><\/span><\/span><\/p>\n<p><b><span style=\"font-size: medium\"><span style=\"color: #000000\"><span style=\"font-family: Calibri\">CDC\u2019s rush to set a \u201csafe\u201d level<\/span><\/span><\/span><\/b><\/p>\n<p><span style=\"font-family: Calibri\"><span style=\"font-size: medium\"><span style=\"color: #000000\">On full display in last week\u2019s press conference was CDC\u2019s remarkable effort to claim that every new data point and every new source of uncertainty that have arisen since it set what Ken Ward calls the \u201cmagic number\u201d of 1 part per million (1 ppm) had already been taken into account.\u00a0\u00a0 The <i>Charleston Gazette<\/i> piece today makes clear that this \u201csafe\u201d level was first derived by CDC late in the evening of January 9, the day the spill was first discovered.<\/span><\/span><\/span><\/p>\n<p><span style=\"font-size: medium\"><span style=\"color: #000000\"><span style=\"font-family: Calibri\">Bear in mind CDC set the 1 ppm level:<\/span><\/span><\/span><\/p>\n<ul>\n<li><span style=\"color: #000000\"><span style=\"font-family: Calibri;font-size: medium\">before CDC had <\/span><\/span><a href=\"https:\/\/blogs.edf.org\/health\/2014\/01\/11\/failed-tsca-collides-with-the-real-world-in-west-virginia-chemical-spill-this-week\/\"><span style=\"color: #0000ff;font-family: Calibri;font-size: medium\">any data other than a single median lethal dose (LD50) value<\/span><\/a><span style=\"font-family: Calibri\"><span style=\"font-size: medium\"><span style=\"color: #000000\"> cited in Eastman Chemical\u2019s 2005 Material Safety Data Sheet for crude MCHM;<\/span><\/span><\/span><\/li>\n<li><span style=\"color: #000000\"><span style=\"font-family: Calibri\"><span style=\"font-size: medium\">before CDC had knowledge of the existence of Eastman\u2019s studies;<\/span><\/span><\/span><\/li>\n<li><span style=\"color: #000000\"><span style=\"font-family: Calibri\"><span style=\"font-size: medium\">before Eastman provided any of those studies to CDC or state officials;<\/span><\/span><\/span><\/li>\n<li><span style=\"color: #000000\"><span style=\"font-family: Calibri;font-size: medium\">before CDC decided to switch from its <\/span><\/span><a href=\"https:\/\/blogs.edf.org\/health\/2014\/01\/13\/west-virginia-officials-trust-shaky-science-in-rush-to-restore-water-service-one-part-per-million-safe-threshold-has-questionable-basis\/\"><span style=\"color: #0000ff;font-family: Calibri;font-size: medium\">indefensible reliance on the LD50 value<\/span><\/a><span style=\"font-family: Calibri\"><span style=\"font-size: medium\"><span style=\"color: #000000\"> to use a \u201cno observed effect level\u201d asserted by Eastman in a 1990 study of \u201cpure MCHM,\u201d a different test substance than that which actually spilled;<\/span><\/span><\/span><\/li>\n<li><span style=\"color: #000000\"><span style=\"font-family: Calibri;font-size: medium\">before CDC recommended that the state <\/span><\/span><a href=\"https:\/\/blogs.edf.org\/health\/2014\/01\/15\/west-virginia-issues-drinking-water-advisory-for-pregnant-women-in-wake-of-chemical-spill\/\"><span style=\"color: #0000ff;font-family: Calibri;font-size: medium\">consider advising pregnant women<\/span><\/a><span style=\"font-family: Calibri\"><span style=\"font-size: medium\"><span style=\"color: #000000\"> not to drink the water until MCHM could not be detected, and the state did so;<\/span><\/span><\/span><\/li>\n<li><span style=\"color: #000000\"><span style=\"font-family: Calibri;font-size: medium\">before the announcement that <\/span><\/span><a href=\"https:\/\/blogs.edf.org\/health\/2014\/01\/21\/yet-another-chemical-identified-as-present-in-west-virginia-chemical-spill\/\"><span style=\"color: #0000ff;font-family: Calibri;font-size: medium\">a second chemical<\/span><\/a><span style=\"font-family: Calibri\"><span style=\"font-size: medium\"><span style=\"color: #000000\"> (actually a mixture called \u201cPPH, stripped\u201d) was present in and had leaked from the tank; and<\/span><\/span><\/span><\/li>\n<li><span style=\"color: #000000\"><span style=\"font-family: Calibri;font-size: medium\">before concerns were raised about CDC\u2019s reliance on a study that <\/span><\/span><a href=\"https:\/\/blogs.edf.org\/health\/2014\/01\/30\/should-we-be-holding-our-breath-waiting-for-more-information-on-risks-of-the-chemical-spilled-in-west-virginia\/\"><span style=\"color: #0000ff;font-family: Calibri;font-size: medium\">only examined MCHM\u2019s toxicity by oral ingestion<\/span><\/a><span style=\"font-family: Calibri\"><span style=\"font-size: medium\"><span style=\"color: #000000\">, in light of its claim that the water would be safe for all uses, including showering and bathing that would involve exposures through inhalation and dermal contact.<\/span><\/span><\/span><\/li>\n<\/ul>\n<p><span style=\"color: #000000;font-family: Calibri;font-size: medium\">A CDC official, when asked about these and other concerns at last week\u2019s press conference, <\/span><a href=\"http:\/\/www.wchstv.com\/newsroom\/rawnews\/raw140205_156.shtml\"><span style=\"color: #0000ff;font-family: Calibri;font-size: medium\">stated unequivocally<\/span><\/a><span style=\"font-family: Calibri\"><span style=\"font-size: medium\"><span style=\"color: #000000\">:\u00a0 \u201cI can tell you:\u00a0 you can use your water however you like, you can drink it, you can bathe in it, you can use it however you like.\u201d\u00a0 In support of that statement, she repeatedly invoked the third of what she called the three 10-fold \u201csafety protection factors\u201d used in CDC\u2019s calculation as sufficient to account for each and every \u201clack of information on specific questions.\u201d<\/span><\/span><\/span><\/p>\n<p><b><span style=\"font-size: medium\"><span style=\"color: #000000\"><span style=\"font-family: Calibri\">Overloading the third 10x factor<\/span><\/span><\/span><\/b><\/p>\n<p><span style=\"color: #000000;font-family: Calibri;font-size: medium\">The third 10-fold factor is what is known as a \u201c<\/span><a href=\"http:\/\/www.epa.gov\/raf\/publications\/pdfs\/rfd-final.pdf\"><span style=\"color: #0000ff;font-family: Calibri;font-size: medium\">database uncertainty factor<\/span><\/a><span style=\"font-family: Calibri\"><span style=\"font-size: medium\"><span style=\"color: #000000\">.\u201d\u00a0 It is intended to be applied where, for example, one has only a single study of a chemical\u2019s toxicity, or studies done only on adult animals, or studies done in only one species of animal.\u00a0 In the present case, all three limitations apply \u2013 more than justifying use of the third 10-fold database uncertainty factor.<\/span><\/span><\/span><\/p>\n<p><span style=\"font-size: medium\"><span style=\"color: #000000\"><span style=\"font-family: Calibri\">But in this case, we also have other major gaps and uncertainties.\u00a0 <\/span><\/span><\/span><\/p>\n<ul>\n<li><span style=\"color: #000000\"><span style=\"font-family: Calibri;font-size: medium\">The <\/span><\/span><a href=\"http:\/\/www.eastman.com\/Literature_Center\/Misc\/Pure_Distilled_MCHM-28-Day_Oral_Feeding_Study.pdf\"><span style=\"color: #0000ff;font-family: Calibri;font-size: medium\">Eastman study that CDC relied on<\/span><\/a><span style=\"font-family: Calibri\"><span style=\"font-size: medium\"><span style=\"color: #000000\"> looked only at short-term exposures and effects (it exposed rats and looked for effects over only a 28-day period).<\/span><\/span><\/span><\/li>\n<li><a href=\"https:\/\/blogs.edf.org\/health\/2014\/01\/26\/epic-fail-in-west-virginia-chemical-spill-poor-information-poor-communications-poor-decisions\/\"><span style=\"color: #0000ff;font-family: Calibri;font-size: medium\">Whether the study actually identified a no-effect level<\/span><\/a><span style=\"color: #000000;font-family: Calibri;font-size: medium\"> \u2013 as claimed by Eastman and apparently accepted at face value by CDC \u2013 has been questioned, with <\/span><a href=\"http:\/\/switchboard.nrdc.org\/blogs\/jsass\/doing_the_math_on_the_west_vir.html\"><span style=\"color: #0000ff;font-family: Calibri;font-size: medium\">some arguing that effects were seen at the lowest dose tested<\/span><\/a><span style=\"font-size: medium\"><span style=\"color: #000000\"><span style=\"font-family: Calibri\"> (which would all by itself justify reducing the \u201csafe\u201d level by factor of 40).\u00a0 <\/span><\/span><\/span><\/li>\n<li><span style=\"color: #000000\"><span style=\"font-family: Calibri\"><span style=\"font-size: medium\">CDC appears never to have gained access to the full study report and underlying data, which is necessary to ascertain whether or not Eastman\u2019s interpretation of the data is correct.<\/span><\/span><\/span><\/li>\n<li><span style=\"color: #000000\"><span style=\"font-family: Calibri\"><span style=\"font-size: medium\">The study, conducted in 1990, used an old protocol dating back to 1981.\u00a0 <\/span><span style=\"font-size: medium\">That protocol <\/span><\/span><\/span><a href=\"http:\/\/www.keepeek.com\/Digital-Asset-Management\/oecd\/environment\/test-no-407-repeated-dose-28-day-oral-toxicity-study-in-rodents_9789264070684-en#page1\"><span style=\"color: #0000ff;font-family: Calibri;font-size: medium\">has been significantly upgraded at least twice<\/span><\/a><span style=\"font-size: medium\"><span style=\"color: #000000\"><span style=\"font-family: Calibri\"> in the intervening two decades to address deficiencies in the original protocol and include important health endpoints such as neurotoxicity, immunotoxicity and endocrine disruption that were clearly not examined in the Eastman study.\u00a0 <\/span><\/span><\/span><\/li>\n<li><span style=\"color: #000000\"><span style=\"font-family: Calibri\"><span style=\"font-size: medium\">The test substance used in the study was pure MCHM, and only contained one (albeit the major one) of the six synthetic chemicals present in the crude MCHM, which was the substance that actually spilled.<\/span><\/span><\/span><\/li>\n<li><span style=\"color: #000000\"><span style=\"font-family: Calibri;font-size: medium\">The study obviously did not examine the toxicity of what we now know was <\/span><\/span><a href=\"https:\/\/blogs.edf.org\/health\/2014\/01\/22\/another-new-wrinkle-on-the-new-mystery-chemical-in-west-virginia-spill\/\"><span style=\"color: #0000ff;font-family: Calibri;font-size: medium\">a second mixture of chemicals \u2013 \u201cPPH, stripped\u201d \u2013 that was also present in the tank<\/span><\/a><span style=\"font-family: Calibri\"><span style=\"font-size: medium\"><span style=\"color: #000000\">, which contains four additional chemicals.<\/span><\/span><\/span><\/li>\n<li><span style=\"color: #000000\"><span style=\"font-family: Calibri\"><span style=\"font-size: medium\">The study considered toxicity by only one route of exposure \u2013 oral ingestion \u2013 despite the obvious potential for exposure by other routes.<\/span><\/span><\/span><\/li>\n<li><span style=\"color: #000000\"><span style=\"font-family: Calibri\"><span style=\"font-size: medium\">The effectiveness of the flushing procedures being employed for MCHM is unstudied and hence unknown.\u00a0 Both sampling data and reports of residual odor indicate the chemical is still present in parts of the distribution system a month after the spill and despite extensive flushing.\u00a0 <\/span><\/span><span style=\"font-family: Calibri\"><span style=\"font-size: medium\">This situation \u2013 coupled with the lack of sampling data at the actual point of exposure, i.e., in residents\u2019 homes \u2013 calls into question what assumptions should be used as to the levels and durations of exposure.<\/span><\/span><\/span><\/li>\n<\/ul>\n<p><span style=\"font-family: Calibri\"><span style=\"font-size: medium\"><span style=\"color: #000000\">To use, as CDC did, a single 10-fold factor to account for all of these myriad data gaps and uncertainties is wholly inadequate.\u00a0 It also deviates from standard risk assessment practice.\u00a0 For example:<\/span><\/span><\/span><\/p>\n<p><span style=\"color: #000000;font-family: Calibri;font-size: medium\">The U.S. Environmental Protection Agency (EPA)\u2019s <\/span><a href=\"http:\/\/www.epa.gov\/raf\/publications\/pdfs\/rfd-final.pdf\"><span style=\"color: #0000ff;font-family: Calibri;font-size: medium\">risk assessment guidance<\/span><\/a><span style=\"font-family: Calibri\"><span style=\"font-size: medium\"><span style=\"color: #000000\"> calls for use of an additional 10-fold uncertainty factor to extrapolate from acute or short-term effects and exposures to longer-term ones.<\/span><\/span><\/span><\/p>\n<p><span style=\"color: #000000;font-family: Calibri;font-size: medium\">Where the only studies available find effects at the lowest dose of a chemical tested, EPA typically uses a 10-fold factor to account for starting with a lowest-observable-adverse-effect level (LOAEL) instead of a no-observable-adverse-effect level (NOAEL); see pp. 46-7 <\/span><a href=\"http:\/\/www.epa.gov\/safewater\/ccl\/pdfs\/reg_determine2\/healthadvisory_ccl2-reg2_dinitrotoluenes.pdf\"><span style=\"color: #0000ff;font-family: Calibri;font-size: medium\">here<\/span><\/a><span style=\"font-family: Calibri\"><span style=\"font-size: medium\"><span style=\"color: #000000\">.<\/span><\/span><\/span><\/p>\n<p><span style=\"font-size: medium\"><span style=\"color: #000000\"><span style=\"font-family: Calibri\">Finally, rather than try to cram the uncertainty due to lack of data on toxicity by other routes of exposure into the same 10-fold database uncertainty factor \u2013 as CDC did \u2013 EPA often applies a separate \u201crelative source contribution\u201d factor (or RSC) to account for the additive nature of other sources of exposure to a given chemical.\u00a0 In the absence of data to the contrary, EPA typically assumes that the exposure route for which data exist \u2013 in this case oral ingestion \u2013 accounts for 20% of total exposure.\u00a0 That amounts to another 5-fold factor.<\/span><\/span><\/span><\/p>\n<p><span style=\"color: #000000;font-family: Calibri;font-size: medium\">While EPA does not always apply the RSC in calculations for shorter-term exposures, it does so in setting Provisional Health Advisory values \u201cdeveloped to provide information in response to an urgent or rapidly developing situation;\u201d see EPA\u2019s <\/span><a href=\"http:\/\/water.epa.gov\/action\/advisories\/drinking\/upload\/2009_01_15_criteria_drinking_pha-PFOA_PFOS.pdf\"><span style=\"color: #0000ff;font-family: Calibri;font-size: medium\">Provisional Health Advisories for Perfluorooctanoic Acid (PFOA) and Perfluorooctane Sulfonate (PFOS)<\/span><\/a><span style=\"font-size: medium\"><span style=\"color: #000000\"><span style=\"font-family: Calibri\"> (p. 3).\u00a0 Clearly, CDC could and should have done so in this case. \u00a0<\/span><\/span><\/span><\/p>\n<p><b><span style=\"font-size: medium\"><span style=\"color: #000000\"><span style=\"font-family: Calibri\">CDC still erroneously maintains its 1000-fold \u201cblanket of protection\u201d is highly conservative<\/span><\/span><\/span><\/b><\/p>\n<p><span style=\"color: #000000\"><span style=\"font-size: medium\"><span style=\"font-family: Calibri\">In last week\u2019s press conference, a CDC official doubled down on CDC\u2019s claim that its calculations of the \u201csafe\u201d level were highly conservative.\u00a0 <\/span><\/span><\/span><a href=\"http:\/\/www.wchstv.com\/newsroom\/rawnews\/raw140205_155.shtml\"><span style=\"color: #0000ff;font-family: Calibri;font-size: medium\">Consider these statements made by the official:<\/span><\/a><\/p>\n<p style=\"padding-left: 30px\"><span style=\"font-size: medium\"><span style=\"color: #000000\"><span style=\"font-family: Calibri\">\u201cThe levels are really 1000-fold more protective than those that were shown to cause harm.\u201d<\/span><\/span><\/span><\/p>\n<p style=\"padding-left: 30px\"><span style=\"font-size: medium\"><span style=\"color: #000000\"><span style=\"font-family: Calibri\">\u201cThe blanket of protection we have put of 1000 is an extremely strong blanket of protection and would prevent any harm at the levels.\u201d<\/span><\/span><\/span><\/p>\n<p><span style=\"color: #000000;font-family: Calibri;font-size: medium\">As I have noted in an <\/span><a href=\"https:\/\/blogs.edf.org\/health\/2014\/01\/16\/cdc-finally-describes-its-derivation-of-safe-level-in-wv-spill-but-erroneously-claims-it-to-be-highly-conservative\/\"><span style=\"color: #0000ff;font-family: Calibri;font-size: medium\">earlier post<\/span><\/a><span style=\"font-family: Calibri\"><span style=\"font-size: medium\"><span style=\"color: #000000\">, these statements indicate a fundamental misunderstanding or misrepresentation of the nature of, and the intent behind applying, the various uncertainty factors \u2013 which CDC continues to erroneously refer to as \u201csafety factors.\u201d\u00a0 I will repeat here what the National Academy of Sciences, in its 2009 report titled <\/span><i><a href=\"http:\/\/www.nap.edu\/catalog.php?record_id=12209\"><span style=\"color: #0000ff\">Science and Decisions:\u00a0 Advancing Risk Assessment<\/span><\/a><\/i><span style=\"color: #000000\"> has to say on this subject (p. 132, emphases in original):<\/span><\/span><\/span><\/p>\n<p style=\"padding-left: 30px\"><span style=\"font-family: Calibri\"><span style=\"font-size: medium\"><span style=\"color: #000000\">Another problem \u2026 is that the term <i>uncertainty factors<\/i> is applied to the adjustments made to calculate the RfD [reference dose, derived from, e.g., a no-effect level] to address species differences, human variability, data gaps, study duration, and other issues. The term engenders misunderstanding: groups unfamiliar with the underlying logic and science of RfD derivation can take it to mean that the factors are simply added on for safety or because of a lack of knowledge or confidence in the process. That may lead some to think that the true behavior of the phenomenon being described may be best reflected in the unadjusted value and that these factors create an RfD that is highly conservative. But the factors are used to adjust for differences in individual human sensitivities, for humans\u2019 generally greater sensitivity than test animals\u2019 on a milligrams-per-kilogram basis, for the fact that chemicals typically induce harm at lower doses with longer exposures, and so on. At times, the factors have been termed <i>safety factors<\/i>, which is especially problematic given that they cover variability and uncertainty and are not meant as a guarantee of safety.<\/span><\/span><\/span><\/p>\n<p><b><span style=\"font-size: medium\"><span style=\"color: #000000\"><span style=\"font-family: Calibri\">So what should CDC have done?<\/span><\/span><\/span><\/b><\/p>\n<p><a href=\"http:\/\/www.wvgazette.com\/News\/201402080047\"><span style=\"color: #0000ff\"><span style=\"font-family: Calibri\"><span style=\"font-size: medium\">Today\u2019s article in the <i>Charleston Gazette<\/i><\/span><\/span><\/span><\/a><span style=\"font-family: Calibri\"><span style=\"font-size: medium\"><span style=\"color: #000000\"> quotes me saying that state and federal officials &#8220;were faced with the clearly daunting task of having exceedingly limited information to go on as they tried to assess and communicate about the risks of a chemical contaminating the tap water of hundreds of thousands of people.\u201d<\/span><\/span><\/span><\/p>\n<p><span style=\"font-family: Calibri\"><span style=\"font-size: medium\"><span style=\"color: #000000\">I believe that.\u00a0 It was a thankless situation.\u00a0 I also believe, in the face of the extremely limited data available and the enormous uncertainties involved, <i>CDC should have refused to recommend a \u201csafe\u201d level and made clear there was no scientific basis for setting one<\/i>.\u00a0 Instead, CDC and the state of West Virginia should have told affected residents to avoid contact with the water until the chemical could not be detected \u2013 something they did for pregnant women a week into the spill.<\/span><\/span><\/span><\/p>\n<p><span style=\"font-family: Calibri\"><span style=\"font-size: medium\"><span style=\"color: #000000\">As a practical matter, that decision would have effectively applied a 100-fold <b><i>actual <\/i><\/b>safety factor, because the limit of detection for MCHM in the sampling officials have conducted is at 10 parts per billion, a level 100-fold lower than the 1 ppm level.\u00a0 It appears that, with some exceptions, that no-detect level is being achieved in most of the distribution system \u2013 with the major caveat that the lack of sampling in residents\u2019 homes is a remaining large unknown.<\/span><\/span><\/span><\/p>\n<p><span style=\"font-family: Calibri\"><span style=\"font-size: medium\"><span style=\"color: #000000\">While this idea of CDC refusing to set a level may sound extreme to some, it would have actually reflected the available science.\u00a0 It would also have avoided much of the ensuing missteps by and mistrust of government officials that we\u2019ve witnessed.<\/span><\/span><\/span><\/p>\n<p><span style=\"color: #000000;font-family: Calibri;font-size: medium\">In <\/span><a href=\"http:\/\/www.wchstv.com\/newsroom\/eyewitness\/140207_23057.shtml\"><span style=\"color: #0000ff;font-family: Calibri;font-size: medium\">an interview Thursday<\/span><\/a><span style=\"font-family: Calibri\"><span style=\"font-size: medium\"><span style=\"color: #000000\">, Rafael Moure-Eraso, the Chairman and Chief Executive of the U.S. Chemical Safety Board, which is investigating the spill, put it succinctly:\u00a0 \u201cThere should be no MCHM in drinking water\u2026.period.\u00a0 There is no safe level.\u201d<\/span><\/span><\/span><\/p>\n<p>&nbsp;<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Richard Denison, Ph.D., is a Senior Scientist. Today marks exactly a month since what is now said to be 10,000 gallons of \u201ccrude MCHM\u201d \u2013 mixed with what was later found to have included other chemicals \u2013 spilled into West Virginia\u2019s Elk River, contaminated 1,700 miles of piping in the water distribution system for nine &#8230;<\/p>\n","protected":false},"author":100,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[75,44,5009],"tags":[39171,39993,39996],"coauthors":[],"class_list":["post-3031","post","type-post","status-publish","format-standard","hentry","category-environment","category-policy","category-health-science","tag-exposure-vs-hazard","tag-general-interest","tag-wv-chemical-spill"],"acf":[],"aioseo_notices":[],"_links":{"self":[{"href":"https:\/\/blogs.edf.org\/health\/wp-json\/wp\/v2\/posts\/3031","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/blogs.edf.org\/health\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/blogs.edf.org\/health\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/blogs.edf.org\/health\/wp-json\/wp\/v2\/users\/100"}],"replies":[{"embeddable":true,"href":"https:\/\/blogs.edf.org\/health\/wp-json\/wp\/v2\/comments?post=3031"}],"version-history":[{"count":1,"href":"https:\/\/blogs.edf.org\/health\/wp-json\/wp\/v2\/posts\/3031\/revisions"}],"predecessor-version":[{"id":12700,"href":"https:\/\/blogs.edf.org\/health\/wp-json\/wp\/v2\/posts\/3031\/revisions\/12700"}],"wp:attachment":[{"href":"https:\/\/blogs.edf.org\/health\/wp-json\/wp\/v2\/media?parent=3031"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/blogs.edf.org\/health\/wp-json\/wp\/v2\/categories?post=3031"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/blogs.edf.org\/health\/wp-json\/wp\/v2\/tags?post=3031"},{"taxonomy":"author","embeddable":true,"href":"https:\/\/blogs.edf.org\/health\/wp-json\/wp\/v2\/coauthors?post=3031"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}