{"id":2568,"date":"2013-02-19T10:00:27","date_gmt":"2013-02-19T15:00:27","guid":{"rendered":"http:\/\/blogs.edf.org\/nanotechnology\/?p=2568"},"modified":"2014-03-25T10:18:30","modified_gmt":"2014-03-25T15:18:30","slug":"prevention-as-cure-confronting-the-environmental-contributions-to-breast-cancer","status":"publish","type":"post","link":"https:\/\/blogs.edf.org\/health\/2013\/02\/19\/prevention-as-cure-confronting-the-environmental-contributions-to-breast-cancer\/","title":{"rendered":"Prevention as cure: Confronting the environmental contributions to breast cancer"},"content":{"rendered":"<p><em>Sarah Vogel, Ph.D.,<\/em> is Managing Director of EDF&#8217;s Health Program.<\/p>\n<p><span style=\"font-size: medium\"><span style=\"color: #000000\"><span style=\"font-family: Calibri\">Breast cancer is a personal issue for too many of us.\u00a0 For six years I have watched the disease overtake a very dear friend\u2019s life.\u00a0 First diagnosed at 32, she underwent radical treatments\u2014 surgeries, radiation and chemo\u2014 and three years later faced metastatic breast cancer that is now ravaging her body.\u00a0 <\/span><\/span><\/span><\/p>\n<p><span style=\"font-size: medium\"><span style=\"color: #000000\"><span style=\"font-family: Calibri\">She is one of the three million women in the U.S. currently facing, or who have been treated for, for breast cancer.\u00a0 She is also one of a growing number of women under 50 getting the disease with <strong><em>no<\/em> <\/strong>family history of breast cancer.\u00a0 <\/span><\/span><\/span><\/p>\n<p><span style=\"font-size: medium\"><span style=\"color: #000000\"><span style=\"font-family: Calibri\">Many women today live longer with or after the disease due to remarkable advancements in medicine, but treatment is not a path anyone would choose.\u00a0 It takes a heavy emotional and physical toll, and often comes with serious impacts on a women\u2019s life, such as the loss of fertility and the risk of reoccurrence.\u00a0 Medical costs for treatment of breast cancer totaled $17.35 billion in 2012. And even with advances in treatment, in 2012, more than 40,000 women died from the disease.\u00a0\u00a0 <\/span><\/span><\/span><\/p>\n<p><span style=\"font-family: Calibri\"><span style=\"font-size: medium\"><span style=\"color: #000000\">The question every woman must ask is: \u201cWhat can I do to prevent the disease for myself or my daughter?\u201d <!--more--><\/span><\/span><\/span><\/p>\n<p><span style=\"font-family: Calibri\"><span style=\"font-size: medium\"><span style=\"color: #000000\">L<\/span><\/span><\/span><span style=\"font-family: Calibri\"><span style=\"font-size: medium\"><span style=\"color: #000000\">ike virtually all diseases, breast cancer has both genetic and environmental risk factors.\u00a0 Although we can\u2019t alter genes that might make us more susceptible, we can do things to reduce risks in our environment.\u00a0 But to do so, we need to know what those risk factors are. It turns out that some of them come from products we use in our households every day.<\/span><\/span><\/span><\/p>\n<p><span style=\"color: #000000;font-family: Calibri;font-size: medium\">A new <\/span><a href=\"http:\/\/www.niehs.nih.gov\/about\/boards\/ibcercc\/\"><span style=\"color: #0000ff;font-family: Calibri;font-size: medium\">report<\/span><\/a><span style=\"color: #000000;font-family: Calibri;font-size: medium\"> just released by the federal <\/span><a href=\"http:\/\/grants.nih.gov\/grants\/guide\/notice-files\/NOT-ES-11-006.html\"><span style=\"color: #0000ff;font-family: Calibri;font-size: medium\">Interagency Breast Cancer and Environment Research Coordinating Committee<\/span><\/a><span style=\"font-family: Calibri\"><span style=\"font-size: medium\"><span style=\"color: #000000\"> (IBCERCC) details what we know \u2013 and don\u2019t know \u2013 about the environmental contributors to the risk of breast cancer and outlines a much-needed and long-sought blueprint for research that would support breast cancer <strong><em>prevention<\/em><\/strong>. <\/span><\/span><\/span><\/p>\n<p><span style=\"font-size: medium\"><span style=\"color: #000000\"><span style=\"font-family: Calibri\">Faced with rising health care costs and the physical and emotional burdens of the disease, we should heed the words of Ben Franklin: an ounce of prevention is worth a pound of cure.\u00a0\u00a0 <\/span><\/span><\/span><\/p>\n<p><span style=\"font-size: medium\"><span style=\"color: #000000\"><span style=\"font-family: Calibri\">In addition to a detailed review of the state of the science on breast cancer and environmental risk factors, the report made a number of significant recommendations that reflect important characteristics of the breast itself.\u00a0 <\/span><\/span><\/span><\/p>\n<p><span style=\"font-size: medium\"><span style=\"color: #000000\"><span style=\"font-family: Calibri\">The breast is highly dynamic.\u00a0 It undergoes multiple periods of rapid change over the course of a woman\u2019s life: from conception to puberty, pregnancy, lactation and menopause.\u00a0 The breast is also full of hormone receptors.\u00a0 <\/span><\/span><\/span><\/p>\n<p><span style=\"font-size: medium\"><span style=\"color: #000000\"><span style=\"font-family: Calibri\">For these reasons, the Committee recommends greater attention to chemicals with estrogen-like activities and to exposures during the multiple critical windows of breast development.\u00a0 The Committee calls for greater research into the effects of chemical exposures on the breast and the development of chemicals tests to improve our ability to identify breast carcinogens.\u00a0 \u00a0<\/span><\/span><\/span><\/p>\n<p><span style=\"color: #000000;font-family: Calibri;font-size: medium\">It might come as a surprise that the government doesn\u2019t have standard tests for assessing whether a chemical used in an everyday household or personal care product might be a breast carcinogen, let alone require such testing.\u00a0 Breast cancer patients and survivors might find it even more troubling that some chemicals, such as bisphenol A (a chemical I\u2019ve written a <\/span><a href=\"http:\/\/www.ucpress.edu\/book.php?isbn=9780520273580\"><span style=\"color: #0000ff;font-family: Calibri;font-size: medium\">book<\/span><\/a><span style=\"color: #000000;font-family: Calibri;font-size: medium\"> about) used in everyday products like food cans and receipt paper, can mimic the effects of estrogen and interfere with the effectiveness of some <\/span><a href=\"http:\/\/www.cpmc.org\/about\/press\/news2011\/bisphenol-breastcells.html\"><span style=\"color: #0000ff;font-family: Calibri;font-size: medium\">breast cancer treatment drugs<\/span><\/a><span style=\"font-size: medium\"><span style=\"color: #000000\"><span style=\"font-family: Calibri\">.\u00a0\u00a0\u00a0 <\/span><\/span><\/span><\/p>\n<p><span style=\"color: #000000;font-family: Calibri;font-size: medium\">There are promising efforts to develop tests that would detect chemical breast carcinogens.\u00a0 A consortium of researchers, including scientists from the <\/span><a href=\"http:\/\/bcgc.berkeley.edu\/chemical-screening\"><span style=\"color: #0000ff;font-family: Calibri;font-size: medium\">University of California-Berkeley<\/span><\/a><span style=\"color: #000000;font-family: Calibri;font-size: medium\">, the non-profit breast cancer research group at the <\/span><a href=\"http:\/\/www.silentspring.org\/\"><span style=\"color: #0000ff;font-family: Calibri;font-size: medium\">Silent Spring Institute<\/span><\/a><span style=\"color: #000000;font-family: Calibri;font-size: medium\">, and the cross-agency government program <\/span><a href=\"http:\/\/www.ncats.nih.gov\/research\/reengineering\/tox21\/tox21.html\"><span style=\"color: #0000ff;font-family: Calibri;font-size: medium\">Tox21<\/span><\/a><span style=\"color: #000000;font-family: Calibri;font-size: medium\">, are working together on a project to develop chemical testing to better predict breast carcinogens. They described this work at a recent meeting Environmental Defense Fund (EDF) held as part of our new <\/span><a href=\"http:\/\/www.edf.org\/health\/chemical-testing-21st-century\"><span style=\"color: #0000ff;font-family: Calibri;font-size: medium\">initiative<\/span><\/a><span style=\"font-family: Calibri\"><span style=\"color: #000000\"><span style=\"font-size: medium\"> on advancing chemical testing in the 21<\/span><sup><span style=\"font-size: small\">st<\/span><\/sup><span style=\"font-size: medium\"> century to make it more relevant to public health. <\/span><\/span><\/span><\/p>\n<p><span style=\"font-size: medium\"><span style=\"color: #000000\"><span style=\"font-family: Calibri\">To accelerate such testing efforts, however, we need a legal mandate. Few chemicals used in food, personal care products, and household cleaners have undergone any testing for cancer risk, and even fewer have been tested for effects that might occur during critical periods of breast development.\u00a0 This is because the laws governing chemicals used in these products do not require chemical manufacturers to conduct these tests.\u00a0 <\/span><\/span><\/span><\/p>\n<p><span style=\"font-size: medium\"><span style=\"color: #000000\"><span style=\"font-family: Calibri\">Recognizing this fundamental policy failing, the Interagency Breast Cancer and Environment Coordinating Committee\u2019s report echoes calls from prestigious scientific bodies and health organizations to reform chemical policy, including changes to the nation\u2019s main chemical safety law, the Toxic Substances Control Act of 1976 (TSCA), which has not been substantially updated in 37 years. <\/span><\/span><\/span><\/p>\n<p><span style=\"color: #000000;font-family: Calibri;font-size: medium\">The <\/span><a href=\"http:\/\/deainfo.nci.nih.gov\/advisory\/pcp\/annualReports\/pcp08-09rpt\/PCP_Report_08-09_508.pdf\"><span style=\"color: #0000ff;font-family: Calibri;font-size: medium\">President\u2019s Cancer Panel,<\/span><\/a><span style=\"color: #000000;font-family: Calibri;font-size: medium\"> the <\/span><a href=\"http:\/\/www.apha.org\/advocacy\/policy\/policysearch\/default.htm?id=1350\"><span style=\"color: #0000ff;font-family: Calibri;font-size: medium\">American Public Health Association<\/span><\/a><span style=\"color: #000000;font-family: Calibri;font-size: medium\">, the <\/span><a href=\"http:\/\/134.147.247.42\/han\/JAMA\/www.ama-assn.org\/assets\/meeting\/2012a\/a12-515.pdf\"><span style=\"color: #0000ff;font-family: Calibri;font-size: medium\">American Medical Association<\/span><\/a><span style=\"color: #000000;font-family: Calibri;font-size: medium\">, and the <\/span><a href=\"http:\/\/pediatrics.aappublications.org\/content\/early\/2011\/04\/25\/peds.2011-0523.abstract\"><span style=\"color: #0000ff;font-family: Calibri;font-size: medium\">American Academy of Pediatrics<\/span><\/a><span style=\"color: #000000;font-family: Calibri;font-size: medium\"> have made similar recommendations.\u00a0 At <\/span><a href=\"http:\/\/www.edf.org\/health\/chemicals\"><span style=\"color: #0000ff;font-family: Calibri;font-size: medium\">EDF<\/span><\/a><span style=\"color: #000000;font-family: Calibri;font-size: medium\">, we\u2019re working alongside public health, scientific and breast cancer organizations in a diverse and growing <\/span><a href=\"http:\/\/www.saferchemicals.org\/\"><span style=\"color: #0000ff;font-family: Calibri;font-size: medium\">coalition<\/span><\/a><span style=\"font-size: medium\"><span style=\"color: #000000\"><span style=\"font-family: Calibri\"> of groups to support strong chemical policy that protects health.\u00a0 <\/span><\/span><\/span><\/p>\n<p><span style=\"color: #000000;font-family: Calibri;font-size: medium\">Breast cancer is largely a preventable disease.\u00a0 To reduce the risks of chemical exposures, we need tests that accurately detect breast carcinogens, and we need policies that demand such testing.\u00a0 Both are achievable in the near term, but to get there we need to make clear we won\u2019t tolerate the status quo. <\/span><a href=\"http:\/\/www.edf.org\/health\/our-progress-fighting-toxic-chemicals?path=hp&amp;postion=2\"><span style=\"color: #0000ff;font-family: Calibri;font-size: medium\">Make your voice heard<\/span><\/a><span style=\"font-size: medium\"><span style=\"color: #000000\"><span style=\"font-family: Calibri\">.\u00a0 Let\u2019s work to prevent breast cancer and get toxic chemicals out of our products, our homes and our lives.\u00a0 \u00a0<\/span><\/span><\/span><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Sarah Vogel, Ph.D., is Managing Director of EDF&#8217;s Health Program. Breast cancer is a personal issue for too many of us.\u00a0 For six years I have watched the disease overtake a very dear friend\u2019s life.\u00a0 First diagnosed at 32, she underwent radical treatments\u2014 surgeries, radiation and chemo\u2014 and three years later faced metastatic breast cancer &#8230;<\/p>\n","protected":false},"author":9413,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[44,5009,114108],"tags":[5019,39986,39993],"coauthors":[],"class_list":["post-2568","post","type-post","status-publish","format-standard","hentry","category-policy","category-health-science","category-tsca","tag-consumer-products","tag-endocrine-disruption","tag-general-interest"],"acf":[],"aioseo_notices":[],"_links":{"self":[{"href":"https:\/\/blogs.edf.org\/health\/wp-json\/wp\/v2\/posts\/2568","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/blogs.edf.org\/health\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/blogs.edf.org\/health\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/blogs.edf.org\/health\/wp-json\/wp\/v2\/users\/9413"}],"replies":[{"embeddable":true,"href":"https:\/\/blogs.edf.org\/health\/wp-json\/wp\/v2\/comments?post=2568"}],"version-history":[{"count":0,"href":"https:\/\/blogs.edf.org\/health\/wp-json\/wp\/v2\/posts\/2568\/revisions"}],"wp:attachment":[{"href":"https:\/\/blogs.edf.org\/health\/wp-json\/wp\/v2\/media?parent=2568"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/blogs.edf.org\/health\/wp-json\/wp\/v2\/categories?post=2568"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/blogs.edf.org\/health\/wp-json\/wp\/v2\/tags?post=2568"},{"taxonomy":"author","embeddable":true,"href":"https:\/\/blogs.edf.org\/health\/wp-json\/wp\/v2\/coauthors?post=2568"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}