{"id":1592,"date":"2011-09-29T10:42:28","date_gmt":"2011-09-29T15:42:28","guid":{"rendered":"http:\/\/blogs.edf.org\/nanotechnology\/?p=1592"},"modified":"2024-02-12T11:01:18","modified_gmt":"2024-02-12T16:01:18","slug":"expansion-of-my-critique-of-the-acc-tools-persistence-and-bioaccumulation-criteria","status":"publish","type":"post","link":"https:\/\/blogs.edf.org\/health\/2011\/09\/29\/expansion-of-my-critique-of-the-acc-tools-persistence-and-bioaccumulation-criteria\/","title":{"rendered":"Expansion of my critique of the ACC tool&#8217;s persistence and bioaccumulation criteria"},"content":{"rendered":"<p><em>Richard Denison, Ph.D.<\/em><em>, is a Senior Scientist.<\/em><\/p>\n<p>I want to clarify and expand on the discussion in <a href=\"http:\/\/blogs.edf.org\/nanotechnology\/2011\/09\/20\/acc%e2%80%99s-chemical-prioritization-tool-helpful-but-flawed-and-off-the-mark-for-epa-to-use-without-tsca-reform\/\">my last post <\/a>on ACC\u2019s selection of criteria for persistence (P) and bioaccumulation (B).\u00a0 The bottom line remains the same:\u00a0 <em>ACC selected the least conservative values proposed by any authoritative body for these parameters<\/em>.\u00a0 <!--more--><\/p>\n<p>I want here to give a fuller picture of available P and B criteria.\u00a0 It should be noted that there can be multiple types of measures of both P and B, but so as not to overly complicate the discussion, and for comparative purposes, I\u2019m focusing here on:<\/p>\n<ul>\n<li>Values for transformation half-lives for P<\/li>\n<li>Values for fish bioaccumulation factors (BAF) or fish bioconcentration factors (BCF) for B<\/li>\n<\/ul>\n<p>As a reminder, here\u2019s what ACC proposed for these values:<\/p>\n<ul>\n<li>Half-life &lt; 180 days = non-persistent<\/li>\n<li>BAF\/BCF &gt; 5,000 = bioaccumulative<\/li>\n<\/ul>\n<p>So how do those compare to cut-offs established by authoritative bodies?<\/p>\n<p><a href=\"http:\/\/live.unece.org\/trans\/danger\/publi\/ghs\/ghs_rev00\/00files_e.html\">Globally Harmonized System (GHS)<\/a>:<\/p>\n<ul>\n<li>For P, GHS doesn\u2019t use transformation half-life values.<\/li>\n<li>For B, GHS indicates that a fish BCF &lt; 500 is \u201cconsidered as indicative of a low level of bioconcentration.\u201d<\/li>\n<\/ul>\n<p><a href=\"http:\/\/www.epa.gov\/fedrgstr\/EPA-TOX\/1999\/November\/Day-04\/t28888.htm\">EPA\u2019s New Chemicals Program (policy for PBTs)<\/a> and <a href=\"http:\/\/www.epa.gov\/fedrgstr\/EPA-TRI\/1999\/January\/Day-05\/tri34835.htm\">Toxics Release Inventory (TRI) PBT definitions<\/a>:<\/p>\n<ul>\n<li>For P:\n<ul>\n<li>a half-life &gt; 60 days in water is deemed persistent and triggers imposition of testing requirements and controls via a consent order (if B and T criteria are also met)<\/li>\n<li>a half-life &gt; 180 days is deemed highly persistent and triggers a presumptive ban unless demonstrated to be incorrect (if B and T criteria are also met)<\/li>\n<\/ul>\n<\/li>\n<li>For B:\n<ul>\n<li>a fish BAF\/BCF &gt; 1,000 is deemed bioaccumulative and triggers imposition of testing requirements and controls via a consent order (if P and T criteria are also met)<\/li>\n<li>a fish BAF\/BCF &gt; 5,000 is deemed highly bioaccumulative and triggers a presumptive ban unless demonstrated to be incorrect (if P and T criteria are also met)<\/li>\n<\/ul>\n<\/li>\n<\/ul>\n<p><a href=\"http:\/\/www.epa.gov\/dfe\/alternatives_assessment_criteria_for_hazard_eval.pdf\">EPA\u2019s Design for Environment (DfE) Program<\/a>:\u00a0 These are the values that I cited in <a href=\"http:\/\/blogs.edf.org\/nanotechnology\/2011\/09\/20\/acc%e2%80%99s-chemical-prioritization-tool-helpful-but-flawed-and-off-the-mark-for-epa-to-use-without-tsca-reform\/\">my last post<\/a>; they were developed by DfE staff in consultation with other EPA experts and consideration of relevant literature.\u00a0 They were designed to provide greater granularity in P and B rankings to reflect the continuous nature of these chemical properties.<\/p>\n<p><a href=\"http:\/\/guidance.echa.europa.eu\/docs\/guidance_document\/information_requirements_part_c_en.pdf?vers=20_08_08\">EU REACH Regulation Annex XIII<\/a>:<\/p>\n<ul>\n<li>For P:\n<ul>\n<li>a half-life &gt; 40 days in fresh water is deemed persistent<\/li>\n<li>a half-life &gt; 60 days in fresh water is deemed very persistent (vP)<\/li>\n<\/ul>\n<\/li>\n<li>For B:\n<ul>\n<li>a fish BAF\/BCF &gt; 2,000 is deemed bioaccumulative<\/li>\n<li>a fish BAF\/BCF &gt; 5,000 is deemed very bioaccumulative (vB)<\/li>\n<\/ul>\n<\/li>\n<\/ul>\n<p>Finally, it\u2019s worth noting that the <a href=\"http:\/\/www.ipen.org\/ipenweb\/poprc\/criteria.html\">Stockholm Convention on Persistent Organic Pollutants (POPs)<\/a> also has criteria to identify P and B for chemicals for which <strong><em>international bans on production and use are warranted<\/em><\/strong> (when they also meet toxicity criteria) \u2013 which of course goes far beyond mere criteria for prioritizing chemicals for further scrutiny.\u00a0 Here are the POPs criteria:<\/p>\n<ul>\n<li>For P:\u00a0 a half-life &gt; 60 days in fresh water<\/li>\n<li>For B:\u00a0 a fish BAF\/BCF &gt; 5,000<\/li>\n<\/ul>\n<p>It\u2019s clear that ACC\u2019s P and B cut-off values are those representing the most extreme level of concern for these parameters across a range of authoritative U.S. and international bodies.<\/p>\n<p>&nbsp;<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Richard Denison, Ph.D., is a Senior Scientist. I want to clarify and expand on the discussion in my last post on ACC\u2019s selection of criteria for persistence (P) and bioaccumulation (B).\u00a0 The bottom line remains the same:\u00a0 ACC selected the least conservative values proposed by any authoritative body for these parameters.\u00a0<\/p>\n","protected":false},"author":100,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[44],"tags":[39150,39192,39156],"coauthors":[],"class_list":["post-1592","post","type-post","status-publish","format-standard","hentry","category-policy","tag-american-chemistry-council","tag-globally-harmonized-system-ghs","tag-persistant-bioaccumulative-and-toxic-pbt"],"acf":[],"aioseo_notices":[],"aioseo_head":"\n\t\t<!-- All in One SEO 4.9.9 - aioseo.com -->\n\t<meta name=\"description\" content=\"Richard Denison, Ph.D., is a Senior Scientist. I want to clarify and expand on the discussion in my last post on ACC\u2019s selection of criteria for persistence (P) and bioaccumulation (B). The bottom line remains the same: ACC selected the least conservative values proposed by any authoritative body for these parameters. I want here to\" \/>\n\t<meta name=\"robots\" content=\"max-image-preview:large\" \/>\n\t<link rel=\"canonical\" href=\"https:\/\/blogs.edf.org\/health\/2011\/09\/29\/expansion-of-my-critique-of-the-acc-tools-persistence-and-bioaccumulation-criteria\/\" \/>\n\t<meta name=\"generator\" content=\"All in One SEO (AIOSEO) 4.9.9\" \/>\n\t\t<meta property=\"og:locale\" content=\"en_US\" \/>\n\t\t<meta property=\"og:site_name\" content=\"EDF Health - Chemical Concerns \u2013 Insights on Air Pollution, Public Health, and Chemical Safety\" \/>\n\t\t<meta property=\"og:type\" content=\"article\" \/>\n\t\t<meta property=\"og:title\" content=\"Expansion of my critique of the ACC tool\u2019s persistence and bioaccumulation criteria - EDF Health\" \/>\n\t\t<meta property=\"og:description\" content=\"Richard Denison, Ph.D., is a Senior Scientist. I want to clarify and expand on the discussion in my last post on ACC\u2019s selection of criteria for persistence (P) and bioaccumulation (B). The bottom line remains the same: ACC selected the least conservative values proposed by any authoritative body for these parameters. 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I want to clarify and expand on the discussion in my last post on ACC\u2019s selection of criteria for persistence (P) and bioaccumulation (B). The bottom line remains the same: ACC selected the least conservative values proposed by any authoritative body for these parameters. I want here to","og:url":"https:\/\/blogs.edf.org\/health\/2011\/09\/29\/expansion-of-my-critique-of-the-acc-tools-persistence-and-bioaccumulation-criteria\/","article:section":"Health Policy","article:published_time":"2011-09-29T15:42:28+00:00","article:modified_time":"2024-02-12T16:01:18+00:00","article:publisher":"https:\/\/www.facebook.com\/edfhealth","twitter:card":"summary_large_image","twitter:site":"@EDFHealth","twitter:title":"Expansion of my critique of the ACC tool\u2019s persistence and bioaccumulation criteria - EDF Health","twitter:description":"Richard Denison, Ph.D., is a Senior Scientist. I want to clarify and expand on the discussion in my last post on ACC\u2019s selection of criteria for persistence (P) and bioaccumulation (B). The bottom line remains the same: ACC selected the least conservative values proposed by any authoritative body for these parameters. I want here to","twitter:creator":"@EDFHealth"},"aioseo_meta_data":{"post_id":"1592","title":null,"description":null,"keywords":null,"keyphrases":null,"primary_term":null,"canonical_url":null,"og_title":null,"og_description":null,"og_object_type":"default","og_image_type":"content","og_image_url":null,"og_image_width":null,"og_image_height":null,"og_image_custom_url":null,"og_image_custom_fields":null,"og_video":null,"og_custom_url":null,"og_article_section":"Health Policy","og_article_tags":null,"twitter_use_og":true,"twitter_card":"default","twitter_image_type":"default","twitter_image_url":null,"twitter_image_custom_url":null,"twitter_image_custom_fields":null,"twitter_title":null,"twitter_description":null,"schema":{"blockGraphs":[],"customGraphs":[],"default":{"data":{"Article":[],"Course":[],"Dataset":[],"FAQPage":[],"Movie":[],"Person":[],"Product":[],"ProductReview":[],"Car":[],"Recipe":[],"Service":[],"SoftwareApplication":[],"WebPage":[]},"graphName":"","isEnabled":true},"graphs":[],"defaultGraph":"","defaultPostTypeGraph":""},"schema_type":"default","schema_type_options":null,"pillar_content":false,"robots_default":true,"robots_noindex":false,"robots_noarchive":false,"robots_nosnippet":false,"robots_nofollow":false,"robots_noimageindex":false,"robots_noodp":false,"robots_notranslate":false,"robots_max_snippet":null,"robots_max_videopreview":null,"robots_max_imagepreview":"large","priority":null,"frequency":null,"local_seo":null,"breadcrumb_settings":null,"limit_modified_date":false,"ai":null,"created":"2022-09-30 15:10:02","updated":"2025-06-06 01:03:10","seo_analyzer_scan_date":null},"aioseo_breadcrumb":"<div class=\"aioseo-breadcrumbs\"><span class=\"aioseo-breadcrumb\">\n\t\t\t<a href=\"https:\/\/blogs.edf.org\/health\" title=\"Home\">Home<\/a>\n\t\t<\/span><span class=\"aioseo-breadcrumb-separator\">&raquo;<\/span><span class=\"aioseo-breadcrumb\">\n\t\t\t<a href=\"https:\/\/blogs.edf.org\/health\/category\/policy\/\" title=\"Health policy\">Health policy<\/a>\n\t\t<\/span><span class=\"aioseo-breadcrumb-separator\">&raquo;<\/span><span class=\"aioseo-breadcrumb\">\n\t\t\tExpansion of my critique of the ACC tool\u2019s persistence and bioaccumulation criteria\n\t\t<\/span><\/div>","aioseo_breadcrumb_json":[{"label":"Home","link":"https:\/\/blogs.edf.org\/health"},{"label":"Health policy","link":"https:\/\/blogs.edf.org\/health\/category\/policy\/"},{"label":"Expansion of my critique of the ACC tool&#8217;s persistence and bioaccumulation criteria","link":"https:\/\/blogs.edf.org\/health\/2011\/09\/29\/expansion-of-my-critique-of-the-acc-tools-persistence-and-bioaccumulation-criteria\/"}],"_links":{"self":[{"href":"https:\/\/blogs.edf.org\/health\/wp-json\/wp\/v2\/posts\/1592","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/blogs.edf.org\/health\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/blogs.edf.org\/health\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/blogs.edf.org\/health\/wp-json\/wp\/v2\/users\/100"}],"replies":[{"embeddable":true,"href":"https:\/\/blogs.edf.org\/health\/wp-json\/wp\/v2\/comments?post=1592"}],"version-history":[{"count":1,"href":"https:\/\/blogs.edf.org\/health\/wp-json\/wp\/v2\/posts\/1592\/revisions"}],"predecessor-version":[{"id":12643,"href":"https:\/\/blogs.edf.org\/health\/wp-json\/wp\/v2\/posts\/1592\/revisions\/12643"}],"wp:attachment":[{"href":"https:\/\/blogs.edf.org\/health\/wp-json\/wp\/v2\/media?parent=1592"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/blogs.edf.org\/health\/wp-json\/wp\/v2\/categories?post=1592"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/blogs.edf.org\/health\/wp-json\/wp\/v2\/tags?post=1592"},{"taxonomy":"author","embeddable":true,"href":"https:\/\/blogs.edf.org\/health\/wp-json\/wp\/v2\/coauthors?post=1592"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}