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  • Chemical Concerns – Insights on Air Pollution, Public Health, and Chemical Safety

    Lindsay McCormick is a Project Manager.  

    When EPA finalized its framework prioritization rule under TSCA last June, the agency deleted its proposed approach to identifying potential candidate chemicals for prioritization.  EDF had supported EPA’s initial proposed rule, and EPA’s decision to delay this process to allow for additional stakeholder engagement tracks closely with the comments chemical industry groups submitted on that proposed rule.

    EPA is now holding a public meeting on December 11th to discuss its proposed approaches and get input from stakeholders.  As with the upcoming meeting on new chemical reviews, EPA is accepting questions ahead of the meeting.

    In response, EDF submitted a number of questions to the agency on Monday, relating to our concerns in the following areas:

    Read our full list of questions here for more details.

    Have you ever wondered what it would be like to leave Earth?

    Floating around the International Space Station and exploring new worlds may sound exciting, but space travel also poses a unique set of pretty intense health effects. Changes in gravitational force and radiation can cause physical harm to the body, while being in a small, isolated environment can take a toll on mental wellbeing. And that’s just the start of it!

    Since the inception of our national and international space programs, researchers have been studying the myriad effects of spaceflight on health in hopes of developing better countermeasures as we venture farther into space.

    In this episode of our podcast, we talked with Dr. Allie Anderson at the University of Colorado Boulder. Dr. Anderson describes “puffy face bird leg” syndrome (yes, that’s a thing) among other health impacts of space travel and what hot topics are keeping folks in space medicine busy.

    Want more? Subscribe and listen on iTunes or Google Play, or check out Podbean to listen via desktop!

    Jennifer McPartland, Ph.D., is a Senior Scientist with the Health Program.

    [pullquote]Among other things, IRIS chemical reviews are used to inform clean-up decisions at Superfund and other contaminated sites, set standards to ensure clean drinking water, assess health risks from toxic air emissions, and evaluate health risks of chemicals in commerce. These are all legally mandated activities stipulated under different laws to ensure the water we drink, the air we breathe, and the lands where we work, live, and play are safe.[/pullquote]Yesterday, the Senate Committee on Appropriations majority posted their version of the FY2018 Interior, Environment and Related Agencies appropriations bill online (see bill here and accompanying explanatory statement here; see the minority’s summary response here). The legislation lays out spending measures for a number of agencies including the Environmental Protection Agency (EPA).  In releasing the bill yesterday, the majority has bypassed the amendment and markup process.

    Among other cuts, the bill eliminates the EPA Integrated Risk Information System (IRIS) Program. At best a small fraction of its responsibilities – and only one-third of its funding – would be re-allocated to the Office of Chemical Safety and Pollution Prevention (OCSPP).

    If realized, this short-sighted move would be a debacle in terms of protecting public health from harmful chemical exposures.

    [A short fact sheet on IRIS and implications of eliminating it is available here.]

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    Richard Denison, Ph.D., is a Lead Senior Scientist.

    Environmental Defense Fund yesterday submitted questions to EPA that we hope are answered by the agency at the public meeting it is convening on December 6th on changes to its new chemicals reviews.

    Despite providing some new documents in advance of the public meeting, details about EPA’s new policies and practices for reviewing new chemicals under the reforms made to TSCA by the Lautenberg Act remain scant.  We identified a number of serious concerns when these changes were first announced by Administrator Pruitt in a news release issued on August 7 – concerns that the meeting background materials EPA has provided only serve to heighten.

    The questions we submitted today relate to our concerns in the following topics:

    EDF has been raising concerns for some time now over the recent redirection of the new chemicals program starkly away from the approach taken following last year’s enactment of the Lautenberg Act.

    Many of the questions we’ve just submitted were formally submitted by letter to EPA’s Office of Pollution Prevention and Toxics (OPPT) more than 3 months ago, on August 16, 2017.  Unfortunately, we have yet to receive responses to them.  We hope they will be addressed at the December 6th meeting.

    Tom Neltner, J.D.is Chemicals Policy Director and Maricel Maffini, Ph.D., Consultant

    Pursuant to a consent decree with the Natural Resources Defense Council (NRDC), the Environmental Protection Agency (EPA) is developing drinking water regulations to protect fetuses and young children from perchlorate, a toxic chemical that inhibits the thyroid’s ability to make the hormone T4 essential to brain development. The rulemaking is part of a long process that began in 2011 when the agency made a formal determination that Safe Drinking Water Act standards for perchlorate were needed. Under the consent decree, EPA should propose a standard by October 2018.

    In the latest step in that process, EPA’s scientists released a draft report in September that, at long last, answers questions posed by its Science Advisory Board in 2013: does perchlorate exposure during the first trimester reduce production of T4 in pregnant women with low iodine consumption? Does reduction in maternal T4 levels in these women adversely affect fetal brain development? According to EPA’s scientists, the answers are Yes and Yes.

    For several years, EPA and the Food and Drug Administration (FDA) have developed and refined a model that would predict the effect of different doses of perchlorate on levels of T4 in pregnant women. The latest version of the model addresses women during the first trimester, especially those with low iodine intake. This is important because iodine is essential to make T4 (the number four indicates the number of iodine atoms present in the hormone); perchlorate inhibits its transport from the blood into the thyroid. The risk of perchlorate exposure to fetuses in the first trimester is greatest because brain development starts very early and is fully dependent on maternal T4. If the mother gets insufficient iodine to offset the perchlorate inhibition, she will not produce enough T4 for the fetal brain to develop properly. When free T4 (fT4) levels are low but without increase in thyroid stimulating hormone (TSH), the condition is known as hypothyroxinemia. When T4 production is lowered further, the pituitary gland releases TSH to increase T4 production by a feedback loop mechanism.

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    Tom Neltner, J.D.is Chemicals Policy Director and Maricel Maffini, Ph.D., Consultant

    Every 15 years, the Environmental Protection Agency’s (EPA) Office of Pesticide Programs (OPP) reviews the safety of registered pesticides. The current cycle ends in 2022. As part of that process, the agency is evaluating the safety of hypochlorite bleaches. In January 2017, EPA decided it would consider the risks posed by degradation of the hypochlorite into perchlorate.

    This is important for two reasons: 1) degraded bleach is less effective as a pesticide, and 2) perchlorate is a chemical that interferes with the production of thyroid hormone, a critical hormone for fetal and infant brain development.

    On September 22, EPA proposed changes to the pesticide label to minimize the degradation for hypochlorite bleach used to disinfect drinking water, and the agency is accepting comments until November 21, 2017. The label would advise users to:

    EDF submitted comments to EPA supporting EPA’s proposal and requesting specific changes to the proposed language, including making the advice to users mandatory. We also asked the agency to extend the label requirements to hypochlorite bleach used to treat produce and to disinfect food handling equipment. Bleach appears to be one of several significant sources of perchlorate contamination of food. Improving management conditions will reduce degradation and preserve effectiveness regardless of the whether the bleach is used in drinking water or to treat vegetables.

    EPA’s proposal is an interim decision. We also were pleased to see that OPP is committed to continue working with EPA’s Office of Water (OW) in its assessment of the risks of perchlorate to pregnant women and young children. We asked OPP to incorporate the OW’s findings in additional interim registration decisions for all uses of hypochlorite bleaches.