Tag Archives: pesticides

Estimating chemical risk: Breadth (prevalence) may be just as important as depth (magnitude of effect)

Jennifer McPartland, Ph.D., is a Health Scientist.

Earlier this month Dr. David Bellinger at Boston Children’s Hospital published a very interesting paper in Environmental Health Perspectives offering a new way to consider the importance of various risk factors for child neurodevelopment—such as pre-existing medical conditions, poor nutritional status or harmful chemical exposures—at the population level.  “A Strategy for Comparing the Contributions of Environmental Chemicals and Other Risk Factors to Neurodevelopment of Children” argues that, in evaluating the contribution of a risk factor to a health outcome, it is critical to consider not only the magnitude of its effect on the health outcome, but also the prevalence of that risk factor in the population.

Dr. Bellinger argues: “Although a factor associated with a large impact would be a significant burden to a patient, it might not be a major contributor to the population if it occurs rarely.  Conversely, a factor associated with a modest but frequently occurring impact could contribute significantly to population burden.”  The former “disease-oriented” approach has generally been used to estimate the burden of harmful chemical exposures to population health, rather than the latter “population-oriented” approach.  Relying solely on the former approach, he contends, may result in an underestimation of the impact of a chemical exposure or other risk factor on public health.  Read More »

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Exposing our ignorance: EPA study reveals barren exposure data landscape

Jennifer McPartland, Ph.D., is a Health Scientist.

This past November, EPA scientists published a sobering paper, “The exposure data landscape for manufactured chemicals,” in the journal Science of the Total Environment.  The paper reveals how little systematic information we have about human and environmental exposures to the thousands of chemicals in use today.

The aim of the study was “to define important aspects of the [chemical] exposure space and to catalog the available exposure information for chemicals being considered for analysis as part of the U.S. EPA ToxCast screening and prioritization program.”  Its conclusion:  “The results suggest that currently available exposure data are insufficient to provide the evidence base required to inform risk assessment and public health decision making.”  Not good, but not surprising.  Read on for more detail. Read More »

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ECHA adds seven more Substances of Very High Concern to REACH Candidate List

Allison Tracy is a Chemicals Policy Fellow. Richard Denison, Ph.D., is a Senior Scientist.

The European Chemicals Agency (ECHA) issued a press release on Tuesday announcing the addition of seven chemicals to the Candidate List of Substances of Very High Concern (SVHC) under the European Union’s REACH Regulation.  [Update 6/20/11:  The formal addition of these substances to the candidate list, the initial announcement of which this post addressed, happened today.  See ECHA's press release, which also contains some additional information about the uses of these chemicals.  The full candidate list including these seven substances is available here.]

All of the chemicals are officially classified as Carcinogenic, Mutagenic or Reproductive toxicants (CMRs).  Their addition brings the total number of chemicals on the Candidate List to 53.  Adding a chemical to REACH’s Candidate List is the first step toward subjecting it to REACH’s Authorization process, whereby the chemical can be used only if specifically authorized by EU authorities.

In this brief post we present a bit more information on these latest seven SVHCs, including the extent of their presence in U.S. commerce and their main uses.  Read More »

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Pediatricians: Reform TSCA to protect kids. ACC responds (a la W.C. Fields): We love kids, too

Richard Denison, Ph.D., is a Senior Scientist.

A long-awaited and full-throated endorsement of comprehensive reform of the Toxic Substances Control Act (TSCA) from the venerable American Academy of Pediatricians (AAP) was published online yesterday in the journal Pediatrics.

Right down the line, the AAP’s 8-page policy statement calling for a wholesale overhaul of TSCA mirrors the recommendations of health and environmental advocates, academic researchers and just about anyone else who has paid attention to the mounting body of evidence documenting the linkages between rising chemical exposures and adverse effects on the health of our population, especially the most vulnerable among us:  the developing fetus, infants and young children.

The AAP’s recommendations also closely track key provisions in TSCA reform bills introduced last year in both Houses of Congress as well as the Safe Chemicals Act of 2011 just re-introduced in the U.S. Senate this month.

This latest statement from the Academy adds it to the list of other major medical and health associations that have previously called on Congress to  revamp TSCA, including the American Medical Association, the American Public Health Association and the American Nurses Association.

Given this growing chorus, it is perhaps not surprising that the American Chemistry Council (ACC) would seek to worm its way in to claim that it, too, loves kids and supports TSCA reform.

But dig a bit deeper, and what is most striking is that ACC stridently opposes essentially every element of TSCA reform called for by the American Academy of Pediatrics.  Read More »

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Do these chemicals make me look fat?

Jennifer McPartland, Ph.D., is a Health Scientist.

My colleague Richard Denison at EDF ended his last blog post asking, “The new study [Environmental Chemicals in Pregnant Women in the US: NHANES 2003-2004] leaves me with one question:  How many more such wake-up calls do we need before our government enacts policies to ensure the safety of chemicals to which we are exposed?”

Maybe this will help shake us awake!  The obesity epidemic in the United States is increasing at alarming rates.   So too is an associated disease, type 2 diabetes.  Researchers have attributed 70% of the risk associated with developing type 2 diabetes with being overweight or obese, a risk that increases by 4.5% for every 2.2 pounds of weight gained over 10 years.

A healthy diet and hitting the gym should keep these diseases at bay, right?  Certainly proper nutrition and exercise are good and important habits for controlling our weight and maintaining overall health.  But what if, despite all such efforts, there are contributing factors outside of our control, and even outside of our genetic makeup?  And what if those potential factors are found in us, on us, and all around us?

New research suggests that chemicals found in our environment and in everyday products may play a significant role in packing on the pounds.  Read More »

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New study demands far more than a pregnant pause: Expectant women carry dozens of toxic chemicals in their bodies

Richard Denison, Ph.D., is a Senior Scientist.

A long-awaited study documenting the presence of multiple toxic chemicals in the bodies of pregnant women was published today in Environmental Health Perspectives.  The study, conducted by researchers at Program on Reproductive Health and the Environment at the University of California, San Francisco, analyzed the most recent comprehensive biomonitoring data collected by the Centers for Disease Control (CDC) as part of its national human biomonitoring program.

The new study found widespread exposure of pregnant women to a large fraction of the chemicals for which biomonitoring is conducted, including chemicals that are currently in widespread use, such as brominated flame retardants (known as PBDEs) used in furniture foam and plastics, perfluorinated chemicals (PFCs) used in everything from packaging to textiles, and a pervasive environmental contaminant used in rocket fuel (perchlorate).

In particular the study noted:  “Certain PCBs, organochlorine pesticides, PFCs, phenols, PBDEs, phthalates, polycyclic aromatic hydrocarbons (PAHs) and perchlorate were detected in 99 to 100% of pregnant women.” (emphasis added)  Read More »

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Regulating nano-silver as a pesticide

John BalbusCal Baier-Anderson, Ph.D., is a Health Scientist.

In May 2008, the International Center for Technology Assessment (ICTA) submitted a petition to EPA requesting that it regulate nano-silver used in products as a pesticide under the Federal Insecticide, Fungicide, and Rodenticide Act (FIFRA).  The petition calls on EPA to take the following specific actions:

  1. Classify nano-silver as a pesticide.
  2. Determine that nano-silver is a new pesticide and require its registration as such.
  3. Analyze the potential risks of nano-silver to human health and the environment.
  4. Take enforcement actions against nano-silver-containing products being sold illegally without EPA approval under FIFRA. Read More »

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