Nanotechnology Notes

Our experts' views on nano news

Posts in 'Inhalation'

Yes, Virginia, inhaled carbon nanotubes do cause lung granulomas

Richard Denison, Ph.D., is a Senior Scientist.

My last post identified two Section 8(e) "substantial risk" notices pertaining to carbon nanotubes, one submitted by BASF, the other by Arkema.  I have in my files one additional Section 8(e) notice for a single-walled carbon nanotube (SWCNT), submitted by DuPont.  With three Section 8(e) notices submitted for different rat pulmonary toxicity studies on carbon nanotubes, it's interesting to compare their results. Read more »

EPA's Nano Consent Order, Part II: What About the Lifecycle?

Richard Denison, Ph.D., is a Senior Scientist.

Since my first post concerning EPA's Consent Order, I've been reflecting further on the management conditions it imposes - or, more accurately, on what conditions it doesn't impose.  The Order's only such conditions address potential worker exposure.  What about the rest of the nanomaterial's lifecycle? Read more »

EPA's Nano Consent Order, Part I: "Sanitized" Transparency is Still Very Revealing

Richard Denison, Ph.D., is a Senior Scientist.

[Part II of this post is available here.] 

Word hit the street today that EPA intends to make public a "sanitized" version of a Consent Order it has negotiated with a producer of multiwalled carbon nanotubes (MWCNTs).  [A link will be provided once available.]  We obtained a copy of the Order, which has redacted all information claimed confidential by the company involved.  What can we learn from this well-scrubbed Order? Read more »

Are Multi-Walled Carbon Nanotubes More Like Asbestos Than We Thought? Part II

John BalbusJohn Balbus, M.D., M.P.H., is Chief Health Scientist.

A new study published today in Nature Nanotechnology finds that multi-walled carbon nanotubes (MWCNTs) cause inflammatory changes in mice that closely resemble those caused by asbestos.  This is the second study in a few months to make this finding.  (I posted on the first, Takagi et al., a few weeks ago.)  So is the case closed on multi-walled carbon nanotubes?  Or is too early to draw conclusions? Read more »

Nanoparticles on the brain?

John BalbusJohn Balbus, M.D., M.P.H., is Chief Health Scientist.

It’s been a worry for engineered nanoparticles. Now, a new study from the Harvard School of Public Health (Suglia et al., 2008) is the first to suggest that particulate air pollution not only damages the lungs and heart, but also may damage the developing brain.

Researchers measured cognitive function in over 200 children in Boston in relation to their residential exposure to traffic-related air pollution by measuring airborne carbon black particles. They found the IQ-lowering effect of higher exposure is comparable to a pregnant mother smoking 10 cigarettes a day or moderate lead exposure. Read more »

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