Comments on: Bacterial Resistance to Silver (Nano or Otherwise) http://blogs.edf.org/nanotechnology/2008/04/29/bacterial-resistance-to-silver-nano-or-otherwise/ Our experts' views on chemical and nano news Thu, 19 Nov 2009 23:21:59 -0800 http://wordpress.org/?v=2.8.5.2 hourly 1 By: Jeffrey S Graham MD http://blogs.edf.org/nanotechnology/2008/04/29/bacterial-resistance-to-silver-nano-or-otherwise/comment-page-1/#comment-166 Jeffrey S Graham MD Thu, 09 Oct 2008 12:05:40 +0000 http://blogs.edf.org/nanotechnology/2008/04/29/bacterial-resistance-to-silver-nano-or-otherwise/#comment-166 I am a urologist and when I head about silver-coated Foley (bladder) catheters it seemed like they could only be a good idea. The thought was to prevent colonization of an indwelling catheter with bacteria, particularly in patients who have catheters permanently. The hope was to minimize symptomatic bladder infections that then become resistant to an increasing number of traditional antibiotics. When I see in the references bacteria commonly seen and treated in urologic practice (E.coli, Enterobacter, Pseudomonas, and Acinetobacter) that have documented ability to develop resistance to silver it is very concerning. To some degree it doesn't limit our treatment options which still just includes the use of traditional po or IV antibiotics, but it does raise the question of whether the additional expense for these catheters is truly of long term benefit or detriment. Jeffrey S Graham MD I am a urologist and when I head about silver-coated Foley (bladder) catheters it seemed like they could only be a good idea. The thought was to prevent colonization of an indwelling catheter with bacteria, particularly in patients who have catheters permanently. The hope was to minimize symptomatic bladder infections that then become resistant to an increasing number of traditional antibiotics. When I see in the references bacteria commonly seen and treated in urologic practice (E.coli, Enterobacter, Pseudomonas, and Acinetobacter) that have documented ability to develop resistance to silver it is very concerning. To some degree it doesn't limit our treatment options which still just includes the use of traditional po or IV antibiotics, but it does raise the question of whether the additional expense for these catheters is truly of long term benefit or detriment.
Jeffrey S Graham MD

]]> By: Ellen Silbergeld http://blogs.edf.org/nanotechnology/2008/04/29/bacterial-resistance-to-silver-nano-or-otherwise/comment-page-1/#comment-138 Ellen Silbergeld Tue, 03 Jun 2008 20:34:14 +0000 http://blogs.edf.org/nanotechnology/2008/04/29/bacterial-resistance-to-silver-nano-or-otherwise/#comment-138 bacteria are quite capable of developing resistance to metals bacteria are quite capable of developing resistance to metals

]]> By: Mathilde Colin http://blogs.edf.org/nanotechnology/2008/04/29/bacterial-resistance-to-silver-nano-or-otherwise/comment-page-1/#comment-116 Mathilde Colin Tue, 06 May 2008 22:37:33 +0000 http://blogs.edf.org/nanotechnology/2008/04/29/bacterial-resistance-to-silver-nano-or-otherwise/#comment-116 Thanks indeed! And for your information, you can also find regularly updated references on Silver Particles (nano or otherwise too) here: http://www.nsec.wisc.edu/NanoRisks/NS--SilverParticles.php Thanks indeed! And for your information, you can also find regularly updated references on Silver Particles (nano or otherwise too) here: http://www.nsec.wisc.edu/NanoRisks/NS–SilverParticles.php

]]> By: Andrew Maynard http://blogs.edf.org/nanotechnology/2008/04/29/bacterial-resistance-to-silver-nano-or-otherwise/comment-page-1/#comment-114 Andrew Maynard Thu, 01 May 2008 10:52:05 +0000 http://blogs.edf.org/nanotechnology/2008/04/29/bacterial-resistance-to-silver-nano-or-otherwise/#comment-114 Cal, Thanks for highlighting this statement an silver and antimicrobial silver, and providing such a comprehensive set of citations addressing it. When I first read the statement that "“bacteria cannot build up a resistance to silver nanoparticles as they can to antibiotics, because of the way the silver nanoparticle attacks" in the Scienceline article, it set all sorts of alarm bells ringing! Andrew Cal,

Thanks for highlighting this statement an silver and antimicrobial silver, and providing such a comprehensive set of citations addressing it. When I first read the statement that "“bacteria cannot build up a resistance to silver nanoparticles as they can to antibiotics, because of the way the silver nanoparticle attacks" in the Scienceline article, it set all sorts of alarm bells ringing!

Andrew

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